Analysis of the influencing factors of benign prostatic hyperplasia complicated with lower urinary tract symptoms
XU Yunfeng1 YOU Zhixin1 LI Yilei1 QIU Feng2▲#br#
1.Department of Urology, Kunshan Second Hospital, Jiangsu Province, Kunshan 215300, China;
2.Department of Urology, the First Affiliated Hospital of Soochow University, Jiangsu Province, Suzhou 215000, China
Abstract：Objective To analyze the influencing factors of benign prostatic hyperplasia complicated with lower urinary tract symptoms. Methods The clinical data of patients admitted to the First Affiliated Hospital of Soochow University from May 2018 to April 2020 which were included 124 patients with benign prostatic hyperplasia complicated with lower urinary tract symptoms (study group) and 133 patients with benign prostatic hyperplasia without lower urinary tract symptoms (control group) were retrospectively analyzed. Using the international prostate symptom score (IPSS), the patients in the study group were recorded as mild group (48 cases, IPSS 0-7 points), moderate group (54 cases, IPSS 8-19 points), and severe group (22 cases, IPSS 20-35 points) according to the severity of the disease. Logistic regression analysis was used to explore the influencing factors of severe lower urinary tract symptoms in patients with benign prostatic hyperplasia. Results The systolic blood pressure, diastolic blood pressure, body mass index (BMI), prostate volume (PV), and fasting blood glucose (FBG) in the study group were higher than those in the control group, while waist circumference and hip circumference were lower than those in the control group, and the differences were highly statistically significant (P ＜ 0.01). There were highly statistically significant differences in BMI, waist-to-hip ratio (WHR), and PV among the three groups (P ＜ 0.05). Further pairwise comparison showed that the severe group had higher BMI, WHR, and PV than those of the mild and moderate groups, and the differences were statistically significant (P ＜ 0.05); the BMI, WHR, and PV of the moderate group were higher than those of the mild group, and the differences were statistically significant (P ＜ 0.05). The levels of WHR, PV, and BMI in the severe group were higher than those in the mild-moderate group, while the proportion of combined lower urinary tract infection was higher than that in the mild-moderate group, and the differences were statistically significant (P ＜ 0.05). Logistic multivariate regression analysis showed that WHR (OR = 3.077), PV (OR = 3.838), and BMI (OR = 2.724) were the influencing factors of severe lower urinary tract symptoms in patients with benign prostatic hyperplasia (P ＜ 0.05). Conclusion WHR, PV, and BMI are risk factors for patients with benign prostatic hyperplasia complicated with lower urinary tract symptoms.
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