Abstract：Objective To investigate the application effect of video assisted thoracoscopy combined with three incisions of neck in the treatment of esophageal cancer. Methods A total of 124 patients diagnosed with esophageal cancer in Rugao Hospital Affiliated to Nantong University from April 2015 to July 2017 were selected as the study subjects. The patients were divided into observation group and control group by random number table method, with 62 cases in each group. The control group was treated with traditional open surgery, and the observation group was treated with video assisted thoracoscopy combined with three incisions of neck. Surgery related indexes were compared between the two groups. The changes in cellular immune function (T cells and cell subsets [CD4+, CD8+, CD4+/CD8+], natural killer [NK] cells, C-reactive protein [CRP]) and lung function (percentage of forced expiratory volume in one second in the expected value [FEV1%], percentage of forced expiratory volume in the expected value [FEV%], percentage of forced vital capacity in the expected value [FVC%], percentage of vital capacity in the expected value in the expected value [VC%], and percentage of maximal voluntary ventilation in the expected value [MVV%]) were compared between the two groups before and after treatment. The incidence of complications and postoperative quality of life scores were compared between the two groups. Results The surgery time, indplacement time of thoracic drainage tube, postoperative hospital stay, and incision length in the observation group were shorter than those in the control group, and the intraoperative blood loss was lower than that in the control group, the differences were statistically significant (P ＜ 0.05). There was no significant difference in the number of dissected lymph nodes between the two groups (P ＞ 0.05). After treatment, the levels of CD4+, CD8+, CD4+/CD8+, NK cells, CRP, MVV%, VC%, FVC%, FEV%, and FEV1% in both groups were lower than those before treatment, and the levels of CD4+, CD8+, CD4+/CD8+, NK cells, MVV%, VC%, FVC%, FEV%, and FEV1% in the observation group were higher than those in the control group, while CRP was lower than that in the control group, the differences were statistically significant (P ＜ 0.05). The total incidence of complications and postoperative quality of life score in the observation group were lower than those in the control group, the differences were statistically significant (P ＜ 0.05). Conclusion Video assisted thoracoscopy combines with three incisions of neck in the treatment of esophageal cancer has good clinical efficacy, value of clinical further promotion.
钱海荣 殷东明 冒楷. 电视胸腹腔镜联合颈部三切口在食管癌患者中的应用效果[J]. 中国医药导报, 2022, 19(14): 105-108.
QIAN Hairong YIN Dongming MAO Kai. Application effect of video assisted thoracoscopy combined with three incisions of neck in patients with esophageal cancer. 中国医药导报, 2022, 19(14): 105-108.
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