Abstract：Objective To evaluate the clinical effect of Tongmai Yangxin Pills on female primary stable microvascular angina (MVA). Methods A total of 577 female patients who were first diagnosed with primary stable MVA in Cangzhou Central Hospital of Hebei Medical University from June 2015 to June 2020 were selected. They were divided into control group (288 cases) and Tongmai Yangxin Pills group (289 cases) by random number table method. The control group was given conventional drug treatment for coronary heart disease, and Tongmai Yangxin Pills group was given Tongmai Yangxin Pills on the basis of control group. All patients were followed up for six months, the significant effective rate and effective rate, rehospitalization rate, and incidence of adverse reaction between two groups were compared, grading of angina by Canadian Society of Cardiology (CCS) and positive rate of electrocardiogram exercise test before and after treatment between two groups were compared. Results The clinical effect in Tongmai Yangxin Pills group was better than that in control group (P ＜ 0.05). After treatment, the grading of angina by CCS in the two groups was lower than that before treatment, and which in Tongmai Yangxin Pills group was lower than that in the control group (P ＜ 0.05). After treatment, the positive rate of electrocardiogram exercise test in both groups was lower than that before treatment, and which in Tongmai Yangxin Pills group was lower than that in control group (P ＜ 0.05). The rehospitalization rate of Tongmai Yangxin Pills group was lower than that in control group (P ＜ 0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P ＞ 0.05). Conclusion Tongmai Yangxin Pills has a significant clinical effect on female patients with primary stable MVA.
闰景漠 张帅勇 苏永健 李杰 颜利求▲ 元柏民▲. 通脉养心丸治疗女性原发性稳定型微血管心绞痛的临床研究[J]. 中国医药导报, 2022, 19(13): 145-148.
RUN Jingmo ZHANG Shuaiyong SU Yongjian LI Jie YAN Liqiu▲ YUAN Bomin▲. Clinical study of Tongmai Yangxin Pills in the treatment of female primary stable microvascular angina#br#. 中国医药导报, 2022, 19(13): 145-148.
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