Investigation on the infection rate and related factors of toxocaracanis among preschoolers in Chongming District, Shanghai
HUNAG Yue1 ZHENG Yan2 NI Yanping1▲
1.Department of Opthalmology, Chongming Branch of Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 202150, China;
2.Department of Opthalmology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China
Abstract：Objective To evaluate the infection of toxocaracanis in preschool children in Chongming district, Shanghai, and analyze the related factors of toxocariasis infection. Methods The questionnaire survey was conducted among 1198 preschool children who studied in six kindergartens in Chongming District, Shanghai in 2018. The serum IgG antibody of toxocaracanis was detected in the children who returned valid questionnaires. The children were divided into infected group and uninfected group according to the detection results, and the influencing factors of toxocaracanis infection were analyzed. Results In this study, 1063 valid questionnaires were collected, with an effective rate of 88.73%. A total of 16 preschool children were positive for toxocariasis antibody, with a positive rate of 1.50%. The proportion of education about toxocaracanis, proportion of children who wash their hands regularly (after returning home, before meals, after using the toilet), and proportion of parents with bachelor degree or abovein infected group were all lower than those in non-infected group, and the differences were statistically significant (P ＜ 0.05). Multifactor analysis showed that receiving education about toxocaracanis, children wash their hands regularly (after returning home, before meals, after using the toilet), and parents with bachelor degree or above were the protective factors of toxocaracanis infection in preschool children (OR ＜ 1, P ＜ 0.05). Conclusion The positive rate of serum toxocaracanis IgG antibody is low in preschool children in Chongming District, Shanghai, which is mainly due to the educational level of parents and good hygienic habits of children.
黄玥1 郑岩2 倪雁萍1▲. 上海市崇明区学龄前儿童犬弓蛔虫感染率及相关因素的调查[J]. 中国医药导报, 2022, 19(11): 64-67.
HUNAG Yue1 ZHENG Yan2 NI Yanping1▲. Investigation on the infection rate and related factors of toxocaracanis among preschoolers in Chongming District, Shanghai. 中国医药导报, 2022, 19(11): 64-67.
[1] Lum FC，Hoskins HD，Moorthy RS，et al. Ocular Toxocariasis-United States，2009—2010 [J]. JAMA，2011，306（3）：261-262.
[2] Arevalo IF，Espinoza RV，Arevalo FA. Ocular toxocariasia [J]. J Pediatr Ophthalmol Strabismus，2012，28（8）：76-86.
[3] Macpherson CN. The epidemiology and public health importance of toxocariasis：a zoonosis of global importance [J]. Int J Parasitol，2013，43（12/13）：999-1008.
[4] 刘亚鲁，张琦，赵培泉.眼弓蛔虫病[J].中华眼底病杂志，2014，30（1）：112-114.
[5] Taylor MRH. The epidemiology of ocular toxocariasis [J]. J Helminthol，2001，75（2）：109-118.
[6] Khademvatan S，Rahim F，Tavalla M，et al. PCR-based molecular characterization of Toxocara spp.using feces of stray cats：a study from Southwest Iran [J]. PLoS One，2013，8（6）：265-293.
[7] 白海鹏，孙维敏，柴运佳，等.眼弓蛔虫病的研究进展[J].疾病监测与控制，2014，8（9）：558-559.
[8] Moreira GM，Telmo Pde L，Mendon?觭a M，et al. Human toxocariasis：current advances in diagnostics，treatment，and interventions [J]. Trends Parasitol，2014，30（9）：456-464.
[9] Good B，Holland CV，Taylor MRH，et al. Ocular Toxocariasis in Schoolchildren[J]. Clin Infect Dis，2004，39（2）：173-174.
[10] Marmor M，Michael L，Glickman L，et al. Toxocara canis infection of children：epidemiologic and neuropsychologic findings [J]. Am J Public Health，1987，77（5）：554-559.
[11] 速尼·J·加尔格.Wills临床眼科彩色图谱及精要：葡萄膜炎[M].天津：天津科技翻译出版社，2015：227-230.
[12] Farmer A，Beltran T，Choi YS. Prevalence of Toxocara species infection in the U.S.：results from the National Health and Nutrition Examination Survey，2011—2014 [J]. PLoS Negl Trop Dis，2017，11（7）：e0005818.
[13] Overgaauw PA. Veterinary and public health aspects of toxocara spp [J]. Vet Parasitol，2013，193：398-403.
[14] 卢祖鹏，张翔，李旌，等.上海市杨浦区学龄前儿童犬首弓蛔虫的感染情况及环境中犬首弓蛔虫的存在情况调查[J].上海交通大学学报（医学版），2019，39（12）：1451-1455.
[15] Luo ZJ，Wang GX，Yang CI，et al. Detection of circulating antigens and antibodies in Toxocara canis infection among children in Chengdu，China [J]. J Parasitol，1999， 85（2）：252-256.
[16] Cilla G，Pérez-Trallero E，Gutiérrez C，et al. Seroprevalence of Toxocara infection in middle-class and disadvantaged children in northern Spain [J]. Eur J Epidemiol，1996，12（5）：541-543.
[17] Kroten A，Toczylowski K，Kiziewicz B，et al. Environmental contamination with Toxocara eggs and seroprevalence of toxocariasis in children of northeastern Poland [J]. Parasitol Res，2016，115（1）：205-209.
[18] Kwon SI，Lee JP，Park SP，et al. Ocular toxocariasis in korea [J]. Jpn J Ophthalmol，2011，55：143-147.
[19] Cortez RT，Ramirez G，Collet LV，et al. Ocular parasitic diseases：a review on toxocariasis and diffuse unilateral subacute neuroretinitis [J]. J Pediatr Ophthalrnol Strabismus，2011，48（2）：204-213.
[20] Campbell JP. Wilkinson CPo Imaging in the diagnosis and management of ocular toxocariasis [J]. Int Ophthalmol Clin，2012，52（8）：145-153.
[21] Magnaval JF，Glickman LT，Dorchies P，et al. Highlights of human toxocariasis [J]. Korean J Parasitol，2001，1（2）：1-11.
[22] Hashida N，Ohguro N，Maruyama H. Fuchs’ heterochromic iridocyclitis associated with ocular toxocariasis [J]. J pn J Ophthalmol，2011，55（3）：67-85.
[23] Kodjikian L，Dufour JF，Nguyen AM，et al. Ocular zoonos-es [J]. Expert Rev Ophthalmol，2009，4（1）：331-349.
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