Abstract：Patients with radiotherapy for malignant tumors have metabolic disorders of organism, radiation side effects, and psychological conditions due to their own diseases, vulnerable to malnutrition, which affect the therapeutic effect, quality of life, and overall survival situation. Compliant and reasonable tumor nutritional treatment can greatly improve the survival treatment and treatment sensitivity of cancer patients. The nutritional risk screening scale 2002 should be routinely used for patients with tumor radiotherapy to conduct nutritional risk screening, evaluating and monitoring nutritional status before, during, and after radiotherapy. This paper further used the patient-generated subjective global assessment scale for patients at nutritional risk, and classification criteria for acute radiation injury in the radiation therapy oncology group during radiotherapy to determine the next intervention strategy. Tumor patients should adopt the principle of five-step treatment according to the degree of malnutrition. The strengthening of clinical nursing work also has great significance and influence on improving patients’ satisfaction with treatment outcome and quality of life, satisfaction, and so on. This article reviews the application progress in the application of nutritional support therapy in patients with malignant tumors undergoing radiotherapy, in order to promote the more standardized implementation of nutritional support in patients with tumor radiotherapy.
王庆兰 潘岑▲ 邓杨清. 营养支持在恶性肿瘤放疗患者中的应用进展[J]. 中国医药导报, 2022, 19(8): 35-38,47.
WANG Qinglan PAN Cen▲ DENG Yangqing. Application progress of nutritional support in patients with radiotherapy for malignant tumors#br#. 中国医药导报, 2022, 19(8): 35-38,47.
[1] 李涛，吕家华，石汉平.放疗患者营养治疗专家共识[J].肿瘤代谢与营养电子杂志，2021，8（1）：29-34.
[2] Trestini I，Carbognin L，Sperduti I，et al. Prognostic impact of early nutritional support in patients affected by locally advanced and metastatic pancreatic ductal adenocarcinoma undergoing chemotherapy [J]. Eur J Clin Nutr，2018， 72（5）：772-779.
[3] Zhai ZW，Zhang KN，Wang C，et al. Comparison of short-term efficacy and perioperative safety between neoadjuvant therapy and total neoadjuvant therapy in patients with locally advanced rectal cancer [J]. Zhonghua Wei Chang Wai Ke Za Zhi，2020，23（3）：274-280.
[4] Caccialanza R，Cereda E，Caraccia M，et al. Early 7-day supplemental parenteral nutrition improves body composition and muscle strength in hypophagic cancer patients at nutritional risk [J]. Support Care Cancer，2019，27（7）：2497-2506.
[5] Pedrazzoli P，Caccialanza R，Cotogni P，et al. The Advantages of Clinical Nutrition Use in Oncologic Patients in Italy： Real World Insights [J]. Healthcare（Basel），2020，8（2）：125-128.
[6] Ikenaga Y，Kusunoki T，Yamaguchi H. Percutaneous Endoscopic Gastrostomy Reduces Aspiration Pneumonia Rate in Stroke Patients with Enteral Feeding in Convalescent Rehabilitation Wards [J]. Prog Rehabil Med，2021，6：20210031.
[7] Lawson JD，Gaultney J，Saba N，et al. Percutaneous feeding tubes in patients with head and neck cancer： rethinking prophylactic placement for patients undergoing chemoradiation [J]. Am J Otolaryngol，2009，30（4）：244-249.
[8] Archid R，Solass W，Tempfer C，et al. Cachexia Anorexia Syndrome and Associated Metabolic Dysfunction in Peritoneal Metastasis [J]. Int J Mol Sci，2019，20（21）：5444-5451.
[9] Miura S，Naito T，Mitsunaga S，et al. A randomized phase Ⅱ study of nutritional and exercise treatment for elderly patients with advanced non-small cell lung or pancreatic cancer：the NEXTAC-TWO study protocol [J]. BMC Cancer，2019，19（1）：528-537.
[10] Wang PY，Li Y，Sun HB，et al. Analysis of the associated factors for severe weight loss after minimally invasive McKeown esophagectomy [J]. Thorac Cancer，2019，10（2）：209-218.
[11] Oh SY，Koh SJ，Baek JY，et al. Validity and Reliability of Korean Version of Simplified Nutritional Appetite Questionnaire in Patients with Advanced Cancer：A Multicenter，Longitudinal Study [J]. Cancer Res Treat，2019， 51（4）：1612-1619.
[12] Jankowska-Polańska B，Polański J，Chabowski M，et al. Influence of Coping Strategy on Perception of Anxiety and Depression in Patients with Non-small Cell Lung Cancer [J]. Adv Exp Med Biol，2020，1251：57-70.
[13] Lu ZH，Fang Y，Liu C，et al. Early Interdisciplinary Supportive Care in Patients With Previously Untreated Metastatic Esophagogastric Cancer：A Phase Ⅲ Randomized Controlled Trial [J]. J Clin Oncol，2021，39（7）：748-756.
[14] 周欣，程敏琼，黄晓萍，等.恶性肿瘤患者放疗期间营养不良发生及危险因素分析[J].国际老年医学杂志，2021， 42（4）：203-207，234.
[15] Wang YJ，Zhang LC，Jin S，et al. Swallowing functional outcomes and nutritional status in head and neck cancer radiotherapy： longitudinal study [J]. BMJ Support Palliat Care，2020，10（4）：452-461.
[16] Shen Y，Zhou YF，He T，et al. Effect of Preoperative Nutritional Risk Screening and Enteral Nutrition Support in Accelerated Recovery after Resection for Esophageal Cancer [J]. Nutr Cancer，2021，73（4）：596-601.
[17] 谢春芳，赵光源，吴正奇.消化系统恶性肿瘤患者，如何进行营养管理[J].东方养生，2021（8）：64-65.
[18] Clavier JB，Antoni D，Atlani D，et al. Baseline nutritional status is prognostic factor after definitive radioche-motherapy for esophageal cancer [J]. Dis Esophagus，2014，27（6）：560-567.
[19] Jain R，Coss C，Whooley P，et al. The Role of Malnutrition and Muscle Wasting in Advanced Lung Cancer [J]. Curr Oncol Rep，2020，22（6）：54-61.
[20] Patel JD，Pereira JR，Chen J，et al. Relationship between efficacy outcomes and weight gain during treatment of advanced，non-squamous，non-small-cell lung cancer patients [J]. Ann Oncol，2016，27（8）：1612-1619.
[21] Meyerhardt JA，Kroenke CH，Prado CM，et al. Association of Weight Change after Colorectal Cancer Diagnosis and Outcomes in the Kaiser Permanente Northern California Population [J]. Cancer Epidemiol Biomarkers Prev，2017，26（1）：30-37.
[22] Kiss N，Baguley BJ，Dalla VJ，et al. Exercise and Nutritional Approaches to Combat Cancer-Related Bone and Muscle Loss [J]. Curr Osteoporos Rep，2020，18（3）：291-300.
[23] 曹晓，杨秋玉，赖鸿皓，等.中国营养指南和专家共识质量评价——基于AGREE Ⅱ和RIGHT工具[J].现代预防医学，2021，48（16）：2918-2923.
[24] Wang YJ，Zhang LC，Jin S，et al. Swallowing functional outcomes and nutritional status in head and neck cancer radiotherapy： longitudinal study [J]. BMJ Support Palliat Care，2020，10（4）：452-461.
[25] De Oliveira LC，Abreu GT，Lima LC，et al. Quality of life and its relation with nutritional status in patients with incurable cancer in palliative care [J]. Support Care Cancer，2020，28（10）：4971-4978.
[26] 高劲，钱立庭.口服营养补充在放疗患者的应用[J].肿瘤代谢与营养电子杂志，2015，2（1）：14-18.
[27] 左浩，闫冬升，李祥伟，等.免疫增强型肠内营养支持联合化疗对老年晚期结直肠癌患者营养状态和免疫功能的影响[J].中国当代医药，2021，28（33）：108-111.
[28] Ravasco P. Nutrition in Cancer Patients [J]. J Clin Med，2019，14（8）：1211.
[29] Britton B，Baker A，Clover K，et al. Heads Up：a pilot trial of a psychological intervention to improve nutrition in head and neck cancer patients undergoing radiotherapy [J]. Eur J Cancer Care（Engl），2017，26（4）：221-225.
[30] Neoh MK，Abu Zaid Z，Mat Daud ZA，et al. Changes in Nutrition Impact Symptoms, Nutritional and Functional Status during Head and Neck Cancer Treatment [J]. Nutrients，2020，12（5）：1225.
[31] 蓝鹏，刘广飞，张赛赛.早期肠内营养支持对重症脑出血患者术后并发症的影响[J].中国医药科学，2021，11（12）：162-165.
[32] 李增宁.恶性肿瘤患者的营养支持治疗[J].中华医学信息导报，2021，36（9）：5.
[33] 刘丽.恶性肿瘤患者营养状况与相关影响因素的研究[J].当代医学，2021，27（20）：95-97.
[34] Eda K，Uzer K，Murat T，et al. The effects of enteral glutamine on radiotherapy induced dermatitis in breast cancer [J]. Clin Nutr，2016，35（2）：436-439.
[35] 王攀姣.规范化营养护理在头颈部肿瘤放疗患者中的应用效果[J].中国民康医学，2021，33（10）：155-157.
[36] Akbar Z，Saeed H，Saleem Z，et al. Dosing errors in total parenteral nutrition prescriptions at a specialized cancer care hospital of Lahore：The role of clinical pharmacist [J]. J Oncol Pharm Pract，2020，26（4）：1-10.
[37] 斯彩娟，王卫光，洪秀芳，等.NRS2002、SGA在恶性肿瘤住院患者营养筛查与评估中的应用[J].浙江医学，2021， 43（11）：1192-1195.
[38] 田俊英.延续性护理干预在乳腺癌患者术后护理中的效果研究[J].中国药物与临床，2021，21（15）：2746-2747.
京公网安备 11010502046598号