Effect of modified Ivor-Lewis operation and Mckeown operation in the treatment of esophageal cancer and its influence on lung function and inflammatory indexes#br#
REN Qiang1 YANG Dabin1 WU Kai1 ZHOU Qianhua2
1.Department of Cardiothoracic Surgery, Huaibei Coal Miners General Hospital of Anhui Province, Anhui Province, Huaibei 235000, China;
2.Department of Cardiothoracic Surgery, Anhui No. 2 Provincal People’s Hospital, Anhui Province, Hefei 230001, China
Abstract：Objective To study the effect of modified Ivor Lewis operation and Mckeown operation in the treatment of esophageal cancer and its influence on lung function and inflammatory indexes. Methods A total of 80 patients with esophageal cancer treated in Huaibei Coal Miners General Hospital of Anhui Province from March 2017 to February 2021 were selected and they were divided into group A and group B by random number table method, with 40 patients in each group. Group A was treated with modified Ivor-Lewis and group B was treated with Mckeown. The changes of perioperative indexes, forced vital capacity (FVC), forced expiratory volume per second /FVC (FEV1/FVC), procalcitonin (PCT), C-reactive protein (CRP), tumor necrosis factor-α (TNF-α), and the incidence of postoperative complications were compared between the two groups. Results The operative time and hospital stay of group A were shorter than that of group B, and the amount of intraoperative blood loss was less than that of group B (P ＜ 0.05). The levels of FVC, FEV1/FVC in group A were higher than those in group B, and the levels of PCT, CRP and TNF-α in serum were lower than those in group B (P ＜ 0.05). The total incidence of complications in group A was lower than that in group B (P ＜ 0.05). Conclusion Compared with Mckeown surgery, the modified Ivor-Lewis surgery have less impact on lung function and inflammatory indexes in patients with esophageal cancer.
任强1 杨大彬1 吴凯1 周乾华2. 改良Ivor-Lewis术式与Mckeown术治疗食管癌的效果及对肺功能、炎症指标的影响[J]. 中国医药导报, 2022, 19(5): 129-132.
REN Qiang1 YANG Dabin1 WU Kai1 ZHOU Qianhua2. Effect of modified Ivor-Lewis operation and Mckeown operation in the treatment of esophageal cancer and its influence on lung function and inflammatory indexes#br#. 中国医药导报, 2022, 19(5): 129-132.
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