A case of gastric adenocarcinoma of the fundic gland type and literature review#br#
KOU Mengjia1 GONG Yucheng1 WANG Zhibin2
1.The Second Clinical Medical School, Beijing University of Chinese Medicine, Beijing 100078, China;
2.Department of Gastroenterology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078, China
Abstract：Gastric adenocarcinoma of the fundic gland type （GA-FG） is a rare tumor that belongs to the new gastric cancer subtype. However, its pathogenesis is not clear, the submucosal infiltration rate is high, but the degree of malignancy is low, lymphatic and venous metastases are less common, and the prognosis is good. In previous reports, GA-FG was mostly submucosal bulge, and the tumor surface was whitish or faded. One case of GA-FG patient reported in this article was admitted to the Department of Spleen, Stomach and Hepatobiliary, Dongfang Hospital, Beijing University of Chinese Medicine on July 30, 2020. The shape of the lesion is a rare flat type, the surface of the tumor is reddish, and there are fundus gland polyps around the lesion. The clinical manifestations were acid reflux heartburn, history of proton pump inhibitor drugs, and endoscopic submucosal dissection treatment. There was no obvious abnormality after the operation. This article reports on the diagnosis and treatment process of patients, reviews and reviews relevant literature, and concludes that the endoscopic diagnosis of GA-FG has not yet formed a consensus and has limitations, and it is very easy to misdiagnose and miss diagnosis. However, it has unique clinicopathological characteristics, combined with morphology and immunophenotype, it can be diagnosed clearly. In terms of etiology, whether proton pump inhibitor is related to the occurrence of GA-FG requires more reports for research and demonstration.
寇梦佳1 宫宇澄1 王志斌2. 胃底腺型胃癌1例并文献复习[J]. 中国医药导报, 2022, 19(3): 174-177.
KOU Mengjia1 GONG Yucheng1 WANG Zhibin2. A case of gastric adenocarcinoma of the fundic gland type and literature review#br#. 中国医药导报, 2022, 19(3): 174-177.
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