Abstract:Gouty nephropathy is one of the most common complications of gout, its incidence rate is gradually increasing. Gouty nephropathy has a serious impact on the life quality in patients with acute attack. At present, Western medicine is still lack specific drugs for the treatment of this disease, and symptomatic treatment is the main principle. Traditional Chinese medicine has certain advantages in the treatment of gouty nephropathy. This paper systematically analyzes one long-term medical case of professor Zhang Yu in treating gouty nephropathy by supplementing spleen and kidney, and analyzes his traditional Chinese medicine syndrome differentiation ideas and clinical treatment experience. This paper summarizes Professor Zhang Yu’s clinical experience in treating gouty nephropathy on the basis of supplementing spleen and kidney, according to the different stages of disease development, combined with the clinical experience of treating gout nephropathy by invigorating dampness and removing turbidity, activating blood and resolving stasis.
常美莹 赵明明 余怡 王如梦 马思佳 张昱. 张昱教授运用补益脾肾法治疗痛风性肾病的长时医案分析[J]. 中国医药导报, 2022, 19(3): 123-126,130.
CHANG Meiying ZHAO Mingming YU Yi WANG Rumeng MA Sijia ZHANG Yu. A long-term case of Professor Zhang Yu’s application of supplementing spleen and kidney in the treatment of gouty nephropathy#br#. 中国医药导报, 2022, 19(3): 123-126,130.
[1] Luo SF,Chin CY,Ho LJ,et al. Monosodium urate crystals induced ICAM-1 expression and cell-cell adhesion in renal mesangial cells:Implications for the pathogenesis of gouty nephropathy [J]. J Microbiol Immunol Infect,2020, 53(1):23-32.
[2] 任桐,朱鹏宇,纪越,等.黄文政教授治疗痛风性肾病临证用药经验总结[J].天津中医药,2020,37(6):645-648.
[3] 陈松鹤,俞鸿晖,方芝嫔,等.中医药治疗痛风性肾病的进展概述[J].中国中医急症,2020,29(10):1877-1880.
[4] 张静文,刘继平.中药治疗高尿酸血症的研究进展[J].医学食疗与健康,2020,18(19):221-222.
[5] 秦笑,孙伟.孙伟教授治疗尿酸性肾病的经验[J].浙江中医药大学学报,2017,41(12):981-983.
[6] 周子正,甘静,李东东,等.尿酸性肾病中医药治疗浅析[J].中国中西医结合肾病杂志,2020,21(1):90-91.
[7] 孙宇洁,奚然然,付书璠,等.中西医治疗痛风性肾病的研究进展[J].风湿病与关节炎,2020,9(8):71-75.
[8] 林志帅,鲁盈.痛风性肾病中医辨治浅述[J].浙江中医杂志,2019,54(5):382.
[9] 朱美凤,张玲,卢佳伟.陈岱治疗痛风性肾病之经验[J].江苏中医药,2021,53(6):31-33.
[10] 马伟忠.刘旭生辨治痛风性肾病的经验[J].江苏中医药,2011,43(5):18-19.
[11] Richette P,Doherty M,Pascual E,et al. 2016 updated EULAR evidence-based recommendations for the management of gout [J]. Ann Rheum Dis,2017,76(1):29-42.
[12] Khanna D,Fitzgerald JD,Khanna PP,et al. 2012 American College of Rheumatology guidelines for management of gout. Part 1:systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia [J]. Arthritis Care Res(Hoboken),2012,64(10):1431-1446.
[13] 俞阳,周奇,张静怡,等.痛风慢性期降尿酸治疗的系统评价再评价[J].中国循证医学杂志,2018,18(12):1368-1375.
[14] 张敬超,林燕.痛风性肾病中医药治疗研究进展[J].中医临床研究,2019,11(9):64-67.
[15] 王银萍,陈静,刘艳华,等.中医药治疗痛风性肾病的研究进展[J].中国中医药现代远程教育,2017,15(13):136-137.
[16] 牟科媛.痛风性肾病中医治法方药与现代医学病理药理探析[J].辽宁中医药大学学报,2014,16(5):11-13.
[17] 邢儒伶.痛风性肾病中医临床治疗概况[J].辽宁中医药大学学报,2009,11(1):181-184.
[18] Tian S,Liu Y,Feng A,et al. Sex-Specific Differences in the Association of Metabolically Healthy Obesity With Hyperuricemia and a Network Perspective in Analyzing Factors Related to Hyperuricemia [J]. Front Endocrinol (Lausanne),2020,11:573452.
[19] Gong M,Wen S,Nguyen T,et al. Converging Relationships of Obesity and Hyperuricemia with Special Reference to Metabolic Disorders and Plausible Therapeutic Implications [J]. Diabetes Metab Syndr Obes,2020,13:943-962.
[20] Ma Z,Wang Y,Xu C,et al. Obesity-Related Genetic Variants and Hyperuricemia Risk in Chinese Men [J]. Front Endocrinol(Lausanne),2019,10:230.
[21] 于中国.如何计算体重指数?[J].中老年保健,2015,1:46.
[22] 樊长征,洪巧瑜.党参对人体各系统作用的现代药理研究进展[J].中国医药导报,2016,13(10):39-43.
[23] 邵礼梅,许世伟.山药化学成分及现代药理研究进展[J].中医药学报,2017,45(2):125-127.
[24] 陈洁.浅述中药熟地黄[J].中国中医药现代远程教育,2010,8(7):201.
[25] 高宏伟,李玉萍,李守超.杜仲的化学成分及药理作用研究进展[J].中医药信息,2021,38(6):73-81.
[26] 宋锦叶,孟立强,李晓玫.黄芪与当归的现代药理学研究进展[J].中国中西医结合肾病杂志,2008,9(9):833-835.
[27] 钱真真,李岩,张菀桐,等.翁维良教授益气温阳活血方治疗心肌梗死反复发作5次长时医案分析[J].天津中医药,2019,36(8):730-735.
[28] 石兆峰,赵晨,胡嘉元,等.构建中医个体化长时程疗效评价方法[J].中国循证医学杂志,2020,20(12):1373-1378.