Comparison of effects and mechanisms of acupoint injection at different tissue levels and research progress#br#
REN Shanjie1 LU Hongxiu2 SU Fan2
1.The First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Shandong Province, Jinan 250355, China;
2.Department of Anesthesiology, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Shandong Province, Jinan 250011, China
Abstract:As a combination of traditional acupuncture and moxibustion with modern injection therapeutic method, acupoint injection has achieved remarkable curative effect. This article reviewed the PubMed, China National Knowledge Infrastructure, and Wanfang database about the acupoint injection level study, found acupoint points are mainly divided into three levels: intradermal, subcutaneous, and muscle layer, the effect of acupoint injection at different level and its physiological anatomy, the nerve distribution and targeting pathway is closely related to, this may be This may be the key to different clinical effects on the same disease at the same acupoint at different levels.
任善洁1 鹿洪秀2 苏帆2. 不同组织层次穴位注射的作用、机制对比及研究进展[J]. 中国医药导报, 2022, 19(2): 29-32.
REN Shanjie1 LU Hongxiu2 SU Fan2. Comparison of effects and mechanisms of acupoint injection at different tissue levels and research progress#br#. 中国医药导报, 2022, 19(2): 29-32.
[1] 邓凯烽,尚鑫阳,朱英,等.穴位注射治疗膝骨关节炎临床疗效和安全性的Meta分析[J].针灸临床杂志,2021, 37(7):48-53.
[2] 钟伟兴,秦庆广,李义凯.穴位注射疗法的若干问题[J].中国针灸,2021,41(7):795-797.
[3] Navarro-Santana MJ,Sanchez-Infante J,Gómez-Chiguano GF,et al. Dry Needling versus Trigger Point Injection for Neck Pain Symptoms Associated with Myofascial Trigger Points:A Systematic Review and Meta-analysis [J]. Pain Med,2021,11:pnab188.
[4] 李瑞午,李翠红,汪智民.足三里穴区不同层次感觉和运动神经元的节段性分布研究[J].中国针灸,2000,20(3):33-35.
[5] 雷玲,章云海,宋长祥,等.应用单光子发射计算机断层扫描观察家兔“风门”穴皮下、皮内及静脉注射核素钼锝的走行通路[J].中国临床康复,2006(15):126-128,193.
[6] Liu SB,Wang ZF,Ma QF,et al. Somatotopic Organization and Intensity Dependence in Driving Distinct NPY-Expressing Sympathetic Pathways by Electroacupuncture [J]. Neuron,2020,108(3):436-450.
[7] Lambert PH,Laurent PE. Intradermal vaccine delivery:will new delivery systems transform vaccine administration? [J]. Vaccine,2008,26(26):3197-3208.
[8] Huang M,Wang X,Xing B,et al. Critical roles of TRPV2 channels,histamine H1 and adenosine A1 receptors in the initiation of acupoint signals for acupuncture analgesia [J]. Sci Rep,2018,8(1):6523.
[9] 谭春凤,刘建浩,黄文灵,黄建福.穴位注射对小儿过敏性紫癜疗效、免疫功能及炎性因子的影响[J].上海针灸杂志,2021,40(6):756-761.
[10] 刘美君,赖劲东,张伟.早期应用夹脊穴穴位注射治疗胸腰部带状疱疹神经痛的有效性和安全性研究[J].中华中医药杂志,2021,36(7):4402-4404.
[11] 黄培炜.基于氧化应激及炎症反应探讨尺泽穴位注射NS对COPD大鼠的作用机制[D].福州:福建中医药大学,2021.
[12] 姚劲松,陈百先,朱贻盛.穴位对药物组织分布的影响[J].中医外治杂志,2012,21(5):11-13.
[13] 韩济生.一场关于针刺镇痛的学术争论:十年后的回顾[J].中国疼痛医学杂志,2021,27(5):321-322.
[14] Hogan NC,Anahtar MN,Taberner AJ,et al. Delivery of immunoreactive antigen using a controllable needle-free jet injector [J]. J Control Release,2017,28(258):73-80.
[15] 李丽梅,张志利.臭氧穴位注射联合脉冲射频治疗带状疱疹后遗神经痛的疗效观察[J].上海针灸杂志,2021, 40(5):600-604.
[16] 黄伟,韦春燕,陆华勇,等.夹脊穴加疱疹区皮内注射疼痛液联合加巴喷丁治疗带状疱疹后遗疼痛的研究[J].皮肤病与性病,2020,42(5):638-641.
[17] 祝丽娟,徐亚黎,汪得芳.香薰疗法联合穴位皮内阻滞注射在第一产程中的效果观察[J].甘肃中医药大学学报,2018,35(2):79-83.
[18] 杨鉴英,洪慧闻.小剂量乙型肝炎疫苗穴位注射免疫效果初探[J].中医杂志,1990(7):27.
[19] 段莹.穴位持续皮下胰岛素输注对2型糖尿病血糖和生存质量影响的临床研究[D].成都:成都中医药大学,2018.
[20] 杨花菊.蜂毒穴位注射对偏头痛模型大鼠PACAP、PKA及C-jun的影响[D].北京:北京中医药大学,2021.
[21] Gu J,Yu C,Li S,et al. Promotion on labor process and relief of the low back pain by relaxing pelvic muscle with Shangliao (BL 31) point injection in women using epidural analgesia during labor:A randomized,controlled,clinical trial [J]. Eur J Obstet Gynecol Reprod Biol,2021,26(264):259-265.
[22] Sun Y,Chen H,Wu C. Effect of the medication injection site on treatment efficacy in pediatric cerebral palsy: conventional sites vs acupoints [J]. J Tradit Chin Med,2019,39(5):716-721.
[23] 何燕娜,孟毅,郜娜娜,等.不同途径注射鼠神经生长因子对脑瘫患儿运动发育、脑血流动力学及生化代谢的影响[J].中国针灸,2020,40(8):839-844.
[24] Liao J,Wang T,Dong W,et al. Acupoint injection for nonspecific chronic low back pain:A protocol of systematic review [J]. Medicine,2019,98(29):e16478.
[25] Wang Y,Hou X,Li L,et al. Acupoint injection improves allergic rhinitis by balancing Th17/Treg in allergic rhinitis rats [J]. Zhen Ci Yan Jiu,2019,44(4):276-281.
[26] Kocak AO,Ahiskalioglu A,Sengun E,et al. Comparison of intravenous NSAIDs and trigger point injection for low back pain in ED: A prospective randomized study [J]. Am J Emerg Med,2019,37(10):1927-1931.
[27] 陈永,刘永谱,班素芬,等.血液穴位注射后小鼠的注射部位发生了什么变化?(英文)[J].南方医科大学学报,2020,40(9):1225-1229.
[28] Wang Q,Li M,Hu X,et al. Autologous blood or autologous serum acupoint injection therapy for psoriasis vulgaris: A protocol for a systematic review and meta-analysis [J]. Medicine,2020,99(23):e20555.
[29] Zhang L,Xiao X,Hui R,et al. Autologous whole-blood or autologous serum acupoint injection therapy for chronic urticaria: A systematic review protocol [J]. Medicine,2019,98(25):e16127.
[30] 方琴,李永乐,蔡明阳,等.穴位注射罗哌卡因分娩镇痛对产妇产程及泌乳功能的影响[J].针刺研究,2019,44(6):434-438.
[31] 李孟汉,郭义.穴位注射研究进展与展望[J].针灸临床杂志,2010,26(10):69-72.
[32] 陈晓彦,李滋平.针药相须治疗腰椎间盘突出症经验[J].中国针灸,2019,39(9):977-980.
[33] 李兰,何亚,程碧辉,等.新斯的明足三里穴位注射对比肌肉注射治疗产后尿潴留的Meta分析[J].国际泌尿系统杂志,2019,39(6):989-992.
[34] Yanuck J,Saadat S,Lee JB,et al. Pragmatic Randomized Controlled Pilot Trial on Trigger Point Injections With 1% Lidocaine Versus Conventional Approaches for Myofascial Pain in the Emergency Department [J]. J Emerg Med,2020,59(3):364-370.
[35] 高雪娇.穴位注射辅助治疗对冠心病患者心绞痛疗效的分析[J].中国疗养医学,2021,30(9):947-949.
[36] 于洋,樊宏,程远,等.格拉司琼静脉注射联合氯化钠穴位注射对术后恶心呕吐的影响[J].中华医学杂志,2019, 99(33):2606-2610.