MRI findings of ovarian sex cord-stromal tumor and analysis of clinical pathological features
HUANG Bin1* LIU Yi1 CHEN Yonglu1* CHEN Wenjun2 SONG Ting1▲
1.Department of Radiology, the Third Affiliated Hospital of Guangzhou Medical University, Guangdong Province, Guangzhou 510150, China;
2.Department of Radiology, Guangdong Women and Children′s Hospital, Guangdong Province, Guangzhou 510010, China
Abstract：Objective To investigate the value of magnetic resonance imaging (MRI) diagnosis for ovarian sex cord-stromal tumor, and the correlation of its MRI findings with pathological features. Methods The MRI findings of 30 patients of ovarian sex cord-stromal tumor confirmed by pathological features were retrospectively analyzed in the Third Affiliated Hospital of Guangzhou Medical University from 2012 July to 2017 June. The correlation of imaging features with clinical pathological structural features was analyzed. Results Among the 30 patients of ovarian sex cord-stromal tumor, 22 (73.33%) were thecoma-fibroma folliculi tumor, including 3 patients of fibroma, 8 patients of theca cell tumor, 11 patients of thec-fibroma. The lesions were isointesity or hypointense on T1WI and equal or higher signal on T2WI. Fiber components showed lower signal on T1WI and T2WI, with slight enhancement in 18 cases and moderate enhancement in 3 cases after contrast medium injection. There were 8 (26.67%) cases of granulosa-cell tumors. The lesions were isointesity or hypointense on T1WI and higher signal on T2WI. Cystic walls and septation showed obvious enhancement on contrast-enhanced images. Conclusion MRI has some characteristics to assess and diagnosis ovarian sex cord-stromal tumor, and MRI features of each type of tumor have a certain internal correlation with clinical pathological structural features.
[1] 赵书会，强金伟.卵巢性索间质肿瘤的CT与MRI诊断[J].实用放射学杂志，2011，27（3）：456-458.
[2] Stuart GC，Dawson LM. Update on granulosa cell tumours of the ovary [J]. Curr Opin Obstet Gynecol，2003，15（1）：33-37.
[3] Tamai K，Koyama T，Saga T，et al. MR features of physiologic and benign conditions of the ovary [J]. Eur Radiol，2006，16（12）：2700-2711.
[4] Omori M，Kondo T，Fukushima J，et al. Extraovarian Fibroma With Minor Sex Cord Elements：A Case Report and Literature Review [J]. Int J Surg Pathol，2017，25（5）：472-476.
[5] 李启，原小军，孔建忠，等.卵巢性索间质肿瘤的MRI诊断与鉴别诊断[J].中国中西医结合影像学杂志，2017， 15（1）：92-94.
[6] 武庆利，郭健，徐春华，等.卵巢性索间质肿瘤的低场MR诊断[J].实用放射学杂志，2012，28（7）：1075-1079.
[7] Horta M，Cunha TM，Marques RC，et al. Ovarian Sertoli-Leydig cell tumor with heterologous elements of gastrointestinal type associated with elevated serum alpha-fetoprotein level：an unusual case and literature review [J]. J Radiol Case Rep，2014，8（11）：30-41.
[8] Katoh T，Yasuda M，Hasegawa K，et al. Estrogen-producing endometrioid adenocarcinoma resembling sex cord-stromal tumor of the ovary：a review of four postmenopausal cases [J]. Diagn Pathol，2012，7：164.
[9] Nemcek AA，Fisher MR，Leschorn E，et al. Mixed sex-cord stromal tumor of the testis：evaluation by ultrasonography and magnetic resonance imaging [J]. Urol Radiol，1989，11（3）：186-189.
[10] Horta M，Cunha TM. Sex cord-stromal tumors of the ovary：a comprehensive review and update for radiologists [J]. Diagn Interv Radiol，2015，21（4）：277-286.
[11] 李莉，周恩利.卵泡膜细胞瘤的MRI表现[J].实用放射学杂志，2013，29（5）：852-853.
[12] Kim JY，Jung KJ，Chung DS，et al. Sclerosing stromal tumor of the ovary：MR-pathologic correlation in three cases [J]. Korean J Radiol，2003，4（3）：194-199.
[13] 罗樱，叶建军，杨晓萍，等.卵巢卵泡膜细胞瘤的MRI表现[J].中华临床医师杂志：电子版，2013，7（15）：7251-7253.
[14] 王冬女，葛玲玉，鄢广平，等.卵巢卵泡膜细胞瘤的MRI诊断[J].实用放射学杂志，2008，24（9）：1289-1290.
[15] 粱峰，王明杰，李旭丹，等.卵巢颗粒细胞瘤的MRI表现与病理对照分析[J].浙江医学，2016，38（3）：216-218.
[16] Jung SE，Rha SE，Lee JM，et al. CT and MRI findings of sex cord-stromal tumor of the ovary [J]. AJR Am J Roentgenol，2005，185（1）：207-15.
[17] Metwalley KA，Elsers DA，Farghaly HS，et al. Precocious puberty secondary to a mixed germ cell-sex cord-stromal tumor associated with an ovarian yolk sac tumor：a case report [J]. J Med Case Rep，2012，6：162.
[18] 袁晓春，张贵祥，张在先，等.卵巢性索-间质肿瘤的MRI表现和病理学的关系[J].中国医学计算机成像杂志，2014，20（6）：532-535.
[19] Stein EB，Wasnik AP，Sciallis AP，et al. MR Imaging-Pathologic Correlation in Ovarian Cancer [J]. Magn Reson Imaging Clin N Am，2017，25（3）：545-562.
[20] Outwater EK，Wagner BJ，Mannion C，et al. Sex cord-stromal and steroid cell tumors of the ovary [J]. Radiographics，1998，18（6）：1523-1546.
2018, Vol. 15 
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