The median effective dosage of 0.447% Methansulfonic Ropivacaine for ultrasound-guided infraclavicular brachial plexus nerve block
ZHANG Yinghui1 XI Zilong2 HAN Yunyun3 YI Jingdong4
1.Department of Anesthesia, the Fifth People′s Hospital of Hengshui City, Hebei Province, Hengshui 053000, China;
2.Department of Orthopaedics, the Fifth People′s Hospital of Hengshui City, Hebei Province, Hengshui 053000, China;
3.Department of Ultrasound, the Fifth People′s Hospital of Hengshui City, Hebei Province, Hengshui 053000, China;
4.Department of Lnternal Medicine, the Fifth People′s Hospital of Hengshui City, Hebei Province, Hengshui 053000, China
Abstract:Objective To determine the median effective dosage of 0.447% Methansulfonic Ropivacaine for ultrasound-guided infraclavicular brachial plexus nerve block. Methods From December 2015 to December 2017, 100 cases carried out upper limb surgery in Anesthesia Department of the Fifth People's Hospital of Hengshui City were selected, ASA Ⅰ-Ⅲ level. Subclavian brachial plexus nerve block guided by ultrasound was carried out, in ultrasonic axillary arteriovenous screen real-time imaging, at brachial plexus inside (outside, behind) lateral band, ribs, pleura, chest muscle groups such as size, 0.447% Methansulfonic Ropivacaine was injected after successfull positioning. Dixon sequential method (Up-and-Down) experiment, with 0.447% Methansulfonic Ropivacaine, and 20 mL solution for the initial capacity, if the block effect was complete, reduce 2 mL to the next patient; if the block effect was incomplete, increase 2 mL to the next patient, and so on. Dixon sequential formula was used to calculate the median effective dosage of 0.447% Methansulfonic Ropivacaine and 95% confidence interval (95%CI) in subclavian brachial plexus nerve block guided by ultrasound. Results Upper limb in patients with subclavian brachial plexus nerve block guided by ultrasound, the median effective dosage of 0.447% Methansulfonic Ropivacaine and 95%CI of 17.5 (17.0-18.0) mL. Conclusion 0.447% Methansulfonic Ropivacaine, for patients with upper limb subclavian brachial plexus nerve block guided by ultrasound, median effective dosage is 17.5 mL.