A cross-sectional study of anxiety and depression in patients with knee osteoarthritis
WU Hai1 PANG Jian1,2▲ CHEN Bo2 CAO Yuelong1,2 ZHAN Hongsheng1,2
1.Shi′s Center of Orthopedics and Traumatology, Shuguang Hospital Affiliated to Shanghai University of TCM, Shanghai 201203, China;
2.Institute of Traumatology & Orthopedics, Shanghai Academy of TCM, Shanghai 201203, China
Abstract:Objective To survey the prevalence of anxiety and depressive disorders in patients with knee osteoarthritis (KOA), and examine the interrelationships between demographic factors, anxiety and depression. Methods This is a cross-sectional pilot study. In this study, 156 patients in the Center of Orthopedics and Traumatology of Shuguang Hospital Affiliated to Shanghai University of TCM from August 2016 to October 2017 were selected. They were diagnosed with KOA. The following information ware acquired: age, gender, body mass index (BMI), duration of disease, education, marriage, occupation, employment status, and score of Hospital Anxiety and Depression Scale (HADS). Results Among the 156 patients with KOA, 74 cases had anxiety and (or) depressive symptoms (47.43%). The patients with KOA had higher rates of depression and anxiety compared to the norms of HADS in Shanghai, with statistically significant differences (P < 0.05). In addition, the anxiety and depression symptoms were negatively correlated with age, gender, BMI, duration of disease, education, marriage, occupation and employment status (P > 0.05). Conclusion There is a certain degree of anxiety and depression symptoms in patients with KOA. It is necessary to adopt a muleidisciplinany approach in treating patients with KOA. Furthermore, there are poor correlations between demographic variables and mental symptoms. It suggests that other undiscovered factors may affect anxiety and depression symptoms in KOA.
吴海1 庞坚1,2▲ 陈博2 曹月龙1,2 詹红生1,2. 膝骨关节炎患者焦虑与抑郁情绪的调查[J]. 中国医药导报, 2018, 15(15): 47-50.
WU Hai1 PANG Jian1,2▲ CHEN Bo2 CAO Yuelong1,2 ZHAN Hongsheng1,2. A cross-sectional study of anxiety and depression in patients with knee osteoarthritis. 中国医药导报, 2018, 15(15): 47-50.
[1] 薛庆云,王坤正,裴福兴,等.中国40岁以上人群原发性骨关节炎患病状况调查[J].中华骨科杂志,2015,35(12):1206-1212.
[2] Stubbs B,Aluko Y,Myint PK,et al. Prevalence of depressive symptoms and anxiety in osteoarthritis:a systematic review and meta-analysis [J]. Age Ageing,2016,45(2):228-235.
[3] 王晓信,刘剑,陈燕,等.慢性骨性关节病患者抑郁状态的相关因素分析[J].中国煤炭工业医学杂志,2009,12(11):1725-1726.
[4] 邱贵兴. 骨关节炎诊治指南[C]//2011全国骨关节创伤学术研讨会.2011.
[5] Zigmond AS,Snaith RP. The hospital anxiety and depression scale [J]. Acta Psychiatr Scand,1983,67(6):361-370.
[6] Axford J,Butt A,Heron C,et al. Prevalence of anxiety and depression in osteoarthritis:use of the Hospital Anxiety and Depression Scale as a screening tool [J]. Clinical Rheumatology,2010,29(11):1277-1283.
[7] 孙振晓,刘化学,焦林瑛,等.医院焦虑抑郁量表的信度及效度研究[J].中华临床医师杂志:电子版,2017,11(2):198-201.
[8] Olss?覬n I,Mykletun A,Dahl AA. The hospital anxiety and depression rating scale: a cross-sectional study of psychometrics and case finding abilities in general practice [J]. BMC Psychiatry,2005,5(1):46-49.
[9] 范青,季建林,肖泽萍,等.综合医院焦虑抑郁量表在内科门诊病人中的应用[J].中国心理卫生杂志,2010,24(5):325-328.
[10] Ahn H,Weaver M,Lyon D,et al. Depression and pain in Asian and white Americans with knee osteoarthritis [J]. J Pain,2017,18(10):1229-1236.
[11] Kang HJ,Bae KY,Kim SW,et al. Impact of anxiety and depression on physical health condition and disability in an elderly Korean population [J]. Psychiatry Investig,2017, 14(3):240-248.
[12] Lee AC,Driban JB,Price LL,et al. Responsiveness and minimally important differences for 4 patient-reported outcomes measurement information system short forms:physical function,pain interference,depression,and anxiety in knee osteoarthritis [J]. J Pain,2017,18(9):1096-1110.
[13] Peeler J,Ripat J. The effect of low-load exercise on joint pain,function,and activities of daily living in patients with knee osteoarthritis [J]. Knee,2018 ,25(1):135-145.
[14] K?觟hler O,Benros ME,Nordentoft M,et al. Effect of anti-inflammatory treatment on depression,depressive symptoms,and adverse effects:a systematic review and meta-analysis of randomized clinical trials [J]. JAMA Psychiatry,2014,71(12):1381-1391.
[15] Hochberg MC,Altman RD,April KT,et al. American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand,hip,and knee [J]. Arthritis Care Res,2012,64(4):465-474.
[16] Veronese N,Stubbs B,Solmi M,et al. Association between lower limb osteoarthritis and incidence of depressive symptoms:data from the osteoarthritis initiative [J]. Age Ageing,2017,46(3):470-476.
[17] Rathbun AM,Stuart EA,Shardell M,et al. Dynamic effects of depressive symptoms on osteoarthritis knee pain [J]. Arthritis Care Res,2018,70(1):80-88.
[18] Sharma A,Kudesia P,Shi Q,et al. Anxiety and depression in patients with osteoarthritis:impact and management challenges [J]. Open Access Rheumatol,2016,8(1):103-113.
[19] 杨学青,张铮,党照华,等.心理护理干预对慢性心力衰竭合并抑郁患者的临床研究[J].中国医药导报,2016, 13(31):174-177.
[20] 唐文娟,钱一平,顾康莹,等.联合综合心理干预对复发性抑郁症患者抑郁情绪、生命健康质量及神经递质的影响[J].中国医药导报,2017,14(34):170-173.