Association between non-high-density lipoprotein cholesterol levels and the degree of coronary artery lesion in elderly patients with coronary heart disease
LI Cong GAO Yonghong▲
Department of Cadre Medical, Beijing Aerospace General Hospital, Beijing 100076, China
Abstract：Objective To analysis the association between non-high-density lipoprotein cholesterol (non-HDL-C) levels and the degree of coronary artery lesion in elderly patients with coronary heart disease. Methods A total of 252 elderly patients who underwent coronary angiography and were admitted to Beijing Aerospace General Hospital from July 2020 to July 2021 were selected, fasting venous blood before angiography was collected, four blood lipids were measured, and the non-HDL-C value was further calculated. According to the results of coronary angiography, they were divided into the coronary heart disease group (210 cases) and the non-coronary heart disease group (42 cases), according to the Gensini score, the coronary heart disease group was divided into mild to moderate disease group with 102 cases and severe disease group with 108 cases. Results The levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and non-HDL-C in severe disease group were higher than those in mild to moderate disease group and non-coronary disease group (P＜0.05); while the levels of TC, LDL-C, and non-HDL-C in moderate disease group were higher than those in non-coronary heart disease group (P＜0.05); the high-density lipoprotein cholesterol (HDL-C) in the severe disease group and the mild to moderate disease group was lower than that in non-coronary disease group (P＜0.05). There was no significant difference in TG among the three groups (P＜0.05). The degree of coronary artery lesions was positively correlated with the levels of TC, LDL-C, and non-HDL-C (r=0.669, 0.683, 0.681, P＜0.001); there was a negative correlation with HDL-C level (r=-0.221, P＜0.001), but no correlation with TG level (P＞0.05). Conclusion Non-HDL-C is closely related to the degree of coronary artery disease in elderly patients with coronary heart disease, and the detection is convenient, which can be used as an important indicator for predicting and evaluating the risk of cardiovascular disease.
李聪 高永红▲. 非高密度脂蛋白胆固醇水平与老年冠心病患者冠脉病变程度的相关性分析[J]. 中国医药导报, 2023, 20(8): 66-69.
LI Cong GAO Yonghong▲. Association between non-high-density lipoprotein cholesterol levels and the degree of coronary artery lesion in elderly patients with coronary heart disease. 中国医药导报, 2023, 20(8): 66-69.
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