基于健康体检研究新疆区直机关干部骨量异常的影响因素

doi:10.20047/j.issn1673-7210.2023.30.15

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摘要目的研究在新疆维吾尔自治区人民医院健康体检的新疆区直机关干部骨量异常情况，分析其危险因素，为预防治疗骨质疏松提供参考。方法选取2020年1月至2021年12月在新疆维吾尔自治区人民医院体检的区直机关干部1 102名为研究对象，采用问卷调查法调查研究对象年龄、性别及所患慢性病等基本情况；并对研究对象进行相关身体检查及骨密度检查。根据骨密度检查情况将研究对象分为三组：骨量正常组（861名）、骨量减少组（109名）、骨质疏松组（132名）；采用logistic回归分析研究对象骨量异常的相关危险因素。结果研究对象骨量减少总患病率为9.89%，骨质疏松总患病率为11.98%。三组性别分布、年龄、低密度脂蛋白胆固醇（LDL-C）、25-羟维生素D[25（OH）D]比较，差异有统计学意义（P＜0.05）。logistic回归分析结果显示，25（OH）D是骨量减少的保护因素[OR（95%CI）=0.920（0.888～0.953），P＜0.05]，LDL-C是骨量减少的危险因素[OR（95%CI）= 1.431（1.116～1.835），P＜0.05]；年龄[OR（95%CI）=1.075（1.053～1.098），P＜0.05]、LDL-C[OR（95%CI）=1.334（1.054～1.689），P＜0.05]是骨质疏松的危险因素；25（OH）D[OR（95%CI）=0.914（0.883～0.946），P＜0.05]和男性[OR（95%CI）=0.302（0.160～0.570），P＜0.05]是骨质疏松的保护因素。结论区直机关50岁及以上干部骨质疏松患病率较高，要重视健康体检。

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	杨英1　　王庆2▲

关键词 ：骨质疏松, 影响因素, 健康体检, 健康管理

Abstract：Objective To study the abnormal bone mass of cadres in Xinjiang Uygur Autonomous Region who underwent physical examination in the People’s Hospital of Xinjiang Uygur Autonomous Region, and to analyze its risk factors, so as to provide reference for the prevention and treatment of osteoporosis. Methods A total of 1 102 cadres from the district offices who underwent physical examination in the People’s Hospital of Xinjiang Uygur Autonomous Region from January 2020 to December 2021 were selected as the study subjects. The age, sex, and chronic diseases of the subjects were investigated by questionnaire. Physical examination and bone density examination were performed on the subjects. The subjects were divided into three groups according to bone mineral density examination: normal bone mass group (861 subjects), bone loss group (109 subjects), osteoporosis group (132 subjects); logistic regression was used to analyze the risk factors of abnormal bone mass. Results The total prevalence of osteopenia was 9.89%, while the total prevalence of osteoporosis was 11.98%. There were significant differences in gender distribution, age, low density lipoprotein cholesterol (LDL-C), 25- hydroxyvitamin D[25 (OH) D] among the three groups (P＜0.05). Logistic regression analysis showed that 25 (OH) D was a protective factor for bone loss (OR [95%CI] =0.920 [0.888-0.953], P＜0.05), LDL-C was a risk factor for bone loss (OR [95%CI] =1.431 [1.116- 1.835], P＜0.05); age (OR [95%CI] =1.075 [1.053-1.098], P＜0.05), LDL-C(OR [95%CI] =1.334 [1.054-1.689], P＜0.05) were risk factors for osteoporosis. 25 (OH) D (OR [95%CI] =0.914 [0.883-0.946], P＜0.05) and male (OR [95%CI] =0.302 [0.160- 0.570], P＜0.05) were protective factors for osteoporosis. Conclusion The prevalence rate of osteoporosis of cadres aged 50 and above in the district offices is high, so pay attention to health examination.

Key words： Osteoporosis Influencing factors Physical examination Health management

基金资助:新疆维吾尔自治区卫生健康青年医学科技人才专项科研项目（WJWY-202030）。

通讯作者: ▲通讯作者

作者简介: 杨英（1983-），女，硕士，副主任医师；研究方向：干部保健、健康管理。

引用本文:

杨英1　　王庆2▲. 基于健康体检研究新疆区直机关干部骨量异常的影响因素[J]. 中国医药导报, 2023, 20(30): 76-80,112.
YANG Ying1 WANG Qing2▲. Analysis of influencing factors of abnormal bone mass of Cadres of organs directly under Xinjiang Uygur Autonomous Region. 中国医药导报, 2023, 20(30): 76-80,112.

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https://www.yiyaodaobao.com.cn/CN/10.20047/j.issn1673-7210.2023.30.15 或 https://www.yiyaodaobao.com.cn/CN/Y2023/V20/I30/76