Abstract:Objective To investigate the effect of oblique lumbar interbody fusion (OLIF) and minimal invasive surgery-transforaminal lumbar interbody fusion (MIS-TLIF) in the treatment of degenerative lumbar scoliosis (DLS) combined with lumbar stenosis (LSS). Methods A total of 89 patients with DLS combined with LSS admitted to the Department of Orthopedics of Haian City People’s Hospital, Jiangsu Province from February 2019 to February 2021 were selected and divided into OLIF group (45 cases) and MIS-TLIF group (44 cases) according to the random number table method. The OLIF group was treated with OLIF, and the MIS-TLIF group was treated with MIS-TLIF. The operative blood loss, operation time, 3 d postoperative drainage volume, getting out of bed time, hospitalization time, and the effect at six months after operation were compared between the two groups. Lumbar function (Oswestry disability index [ODI] and Japanese Orthopaedic Association evaluation treatment [JOA] score) were evaluated before and six months after operation, and postoperative complications were counted. Results The operative blood loss and 3 d postoperative drainage volume in OLIF group were lower than those in MIS-TLIF group, and the operative time, getting out of bed time, and hospitalization time were shorter than those in MIS-TLIF group, and the operative effect was better than that in MIS-TLIF group (P<0.05). At six months after operation, ODI was lower than that before operation, and JOA score was higher than that before operation, and ODI in OLIF group was lower than that in MIS-TLIF group, JOA score was higher than that in MIS-TLIF group (P<0.05). The incidence of postoperative complications in OLIF group was lower than that in MIS-TLIF group (P<0.05). Conclusion Compared with MIS-TLIF, OLIF in DLS patients with LSS can improve perioperative indexes, improve operative results, enhance lumbar function, and reduce postoperative complications.