Abstract：Objective To observe the effect of target blood pressure management on nursing effect and prognosis of cerebral aneurysm after interventional surgery. Methods A total of 340 patients with cerebral aneurysm who underwent interventional surgery in Nanjing Hospital Affiliated to Nanjing Medical University from January 2018 to December 2020 were selected. According to the random number table method, they were divided into control group and observation group, with 170 cases in each group. The control group received routine blood pressure management, and the observation group received target blood pressure management. The nursing effect and prognosis of the two groups were compared. Results Overall analysis showed that there were statistically significant differences between groups, time points and interactions in the systolic blood pressure and diastolic blood pressure(P ＜ 0.05). Further pairwise comparison, intra-group comparison: the systolic blood pressure and diastolic blood pressure of the two groups one hour before operation and immediately after operation, and immediately after awakening, and one hour after awakening were significantly (P ＜ 0.05); the systolic blood pressure and diastolic blood pressure in the observation group were lower than those in the control group at the same time (P ＜ 0.05). The incidence of unplanned extubation, abnormal fluctuation of blood pressure, rupture of cerebral aneurysm, and cerebral infarction in the observation group were lower than those in the control group (P ＜ 0.05). The hospital stay in the observation group was shorter than that in the control group (P ＜ 0.05). On postoperative day seven, the Glasgow outcome scale scores of the two groups were better than those before operation, and the observation group was better than the control group (P ＜ 0.05). Conclusion Target blood pressure management plays a role in reducing postoperative blood pressure after cerebral aneurysm intervention, reducing the risk of unplanned extubation, abnormal blood pressure fluctuation, cerebral aneurysm rupture, and cerebral infarction, with lower prognosis of neurological deficit and shorter hospital stay.
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