Abstract：Objective To investigate the influencing factors of poor prognosis in patients with acute cerebral infarction (ACI). Methods From January 2019 to September 2021, 80 ACI patients in Bozhou Hospital of Traditional Chinese Medicine, Anhui Province were selected as the study subjects. They were divided into good prognosis group (≤2 points, 47 cases) and poor prognosis group (＞2 points, 33 cases) according to modified Rankin score (mRS) after treatment. Clinical data were compared between the two groups, and logistic regression was used to analyze the influencing factors of poor prognosis in ACI patients. Results The levels of serum low density lipoprotein-cholesterol (LDL-C), homocysteine (Hcy), and National Institutes of Health stroke scale (NIHSS) score in the poor prognosis group were higher than those in the good prognosis group, and the differences were statistically significant (P ＜ 0.05). Logistic regression model analysis showed that high serum LDL-C and Hcy levels, and high NIHSS score were independent risk factors for poor prognosis in ACI patients (OR ＞ 1, P ＜ 0.05). Conclusion Serum LDL-C and Hcy levels and NIHSS score in patients with ACI are important factors influencing the poor prognosis, which should be paid attention to in clinical practice.
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