Abstract:Objective To explore the effect of health care and disease development origin (DOHaD) concept oriented dietary nursing in patients with gestational diabetes mellitus (GDM). Methods A total of 103 patients with GDM treated in the Second Affiliated Hospital of the Army Medical University from January 2020 to may 2021. They were divided into observation group (52 cases) and control group (51 cases) according to the random number table method. The control group was treated with routine dietary nursing, and the observation group was treated with DOHaD concept oriented dietary nursing. Both groups received nursing intervention from admission to delivery. The blood glucose control effects (fasting plasma glucose [FPG], 2 hour postprandial blood glucose [2hPG] ), self-care ability (self-care ability measurement scale [ESCA] ), the incidence of adverse pregnancy outcomes, dietary compliance and the increase of body mass index (BMI) were compared between the two groups before and after intervention. Results After the intervention, the FPG and 2hPG of the two groups were lower than those of the same group before the intervention, and the observation group was lower than that of the control group, the differences were statistically significant (P < 0.05); the ESCA scores of the two groups were higher than those of the same group before the intervention, and the observation group was higher than that of the control group, the differences were statistically significant (P < 0.05); the incidence of adverse pregnancy outcomes and the increase of BMI in the observation group were lower than those of the control group, the difference was statistically significant (P < 0.05); the diet compliance rate of the observation group was higher than that of the control group, the differences were statistically significant (P < 0.05). Conclusion DOHaD concept oriented dietary nursing can help GDM patients control weight, reduce blood sugar, improve adverse pregnancy outcomes, enhance self-care ability of patients, and improve their dietary compliance.