Abstract：The incidence of acute renal injury (AKI) is high and critical in clinic, clinically the early diagnosis of AKI based on serum creatinine and urine volume is delayed and insufficient. Clinically, biomarkers with high sensitivity and specificity are needed to facilitate the early diagnosis of AKI, so that measures can be taken to reduce renal injury and protect renal function. Some novel biomarkers closely related to the pathogenesis of AKI are gradually being used for early identification, clinical monitoring and prognosis assessment of AKI. This article focuses on the biological functions, research status and application prospects of AKI-related biomarkers discovered in recent years, such as interleukin 24, liver-type fatty acid binding protein, chitinase 3-like protein 1, microRNA, PARK7, and CDH16.
原道川 龚学忠 刘建联 王丹军 李同路. 急性肾损伤相关新型生物标志物的研究进展[J]. 中国医药导报, 2022, 19(1): 44-47.
YUAN Daochuan GONG Xuezhong LIU Jianlian WANG Danjun LI Tonglu. Research progress of new biomarkers related to acute renal injury#br#. 中国医药导报, 2022, 19(1): 44-47.
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