Abstract：Objective To analyze the prescription rules of treating anal sinusitis with traditional Chinese medicine in periodical literature by using traditional Chinese medicine inheritance support system platform. Methods The literatures on traditional Chinese medicine treatment of anal sinusitis published in China National Knowledge Infrastructure, Chinese sci-tech Periodical Full-text Database and Wanfang Database from inception to February 2021 were screened, and the data were input into the traditional Chinese medicine inheritance support system platform. The data analysis module of the software was used to analyze the medication rule of traditional Chinese medicine in the treatment of anal sinusitis, including four nature of drugs, five flavours, channel tropism, drug use frequency, prescription rule and potential new prescription combination. Results A total of 49 prescriptions involving 118 traditional Chinese medicine were included. Drugs were mainly cold drugs (202 times), bitter drugs (263 times), sweet drugs (150 times), spicy drugs (109 times), mainly through the liver meridian (145 times), spleen meridian (132 times), stomach meridian (107 times), lung meridian (99 times). The six most frequently used herbs were amur cork-tree (26 times), liquorice root (21 times), golden thread (18 times), chinese angelica (14 times), garden burnet root (13 times) and lightyellow sophora root (13 times). The first six drug pairs were chinese angelica-unprocessed rehmannia root, liquorice root-orange fruit, chinese angelica-liquorice root , amur cork-tree-garden burnet root, liquorice root-golden thread, dandelion-wild chrysanthemum flower. A total of six core drug combinations for the new formula were excavated. Conclusion At present, the known traditional Chinese medicine prescriptions for the treatment of anal sinusitis are mainly to clear heat and remove diuresis, cool blood and detoxify, and also to soothe liver, promote blood circulation and relieve pain, etc. The core drug combinations and new prescriptions have certain reference value for the theoretical research, new drug development and clinical syndrome differentiation treatment of anal sinusitis.
于大远 刘薇 李雪 刘仍海▲. 基于数据挖掘分析中医药治疗肛窦炎用药规律[J]. 中国医药导报, 2021, 18(34): 126-130.
YU Dayuan LIU Wei LI Xue LIU Renghai▲. Analysis of the medication rule of traditional Chinese medicine in treating anal sinusitis based on data mining#br#. 中国医药导报, 2021, 18(34): 126-130.
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