Effect of acupuncture plus moxibustion in treating chronic fatigue syndrome with yang deficiency of spleen and kidney and its influence on immune function
SUN Yuan
Department of Acupuncture and Moxibustion, Ma’anshan Hospital of Traditional Chinese Medicine, Anhui Province, Ma’anshan 243000, China
Abstract:Objective To investigate the effect of acupuncture plus moxibustion in treating chronic fatigue syndrome (CFS) with yang deficiency of spleen and kidney and its influence on immune function. Methods Eighty patients with CFS with yang deficiency of spleen and kidney admitted to Outpatient Department of Preventive Treatment in Ma’anshan Hospital of Traditional Chinese Medicine from February 2017 to July 2020 were selected as the research subjects. All patients were divided into control group and observation group according to random number table method, with 40 cases in each group. Control group was treated with ordinary acupuncture, and observation group was treated with moxibustion on the basis of control group, once every other day, five times for a course of treatment, six courses of treatment. The curative effect, symptom score, immunoglobulin G (IgG), immunoglobulin A (IgA) and immunoglobulin M (IgM) levels before and after treatment were compared between two groups, and the adverse reaction was observed. Results Total effective rate of observation group was higher than that of control group, the difference was statistically significant (P < 0.05). After treatment, the scores of memory loss, anxiety, insomnia and depression in two groups were lower than those before treatment, and observation group was lower than control group, the differences were statistically significant (P < 0.05). After treatment, the levels of IgG, IgA and IgM in two groups were higher than those before treatment, and observation group was higher than control group, the differences were statistically significant (P < 0.05). There was no obvious adverse reaction in two groups. Conclusion Acupuncture plus moxibustion is an effective and safe in treating CFS with yang deficiency of spleen and kidney, which can effectively improve clinical symptoms and immune function.
孙元. 针刺加艾灸治疗慢性疲劳综合征脾肾阳虚型的效果及对免疫功能的影响[J]. 中国医药导报, 2021, 18(21): 150-152,172.
SUN Yuan. Effect of acupuncture plus moxibustion in treating chronic fatigue syndrome with yang deficiency of spleen and kidney and its influence on immune function. 中国医药导报, 2021, 18(21): 150-152,172.
[1] 王会丽,袁倩,刘瑞芳.针刺联合推拿、运动训练对慢性疲劳综合征患者生活质量的影响[J].陕西中医,2018, 437(5):122-126.
[2] 许艺燕,刘继洪,丁慧,等.耳穴金针疗法治疗气虚质慢性疲劳综合征临床研究[J].中国针灸,2019,39(2):19-23.
[3] Eveng?覽rd B,Schacterle RS,Komaroff AL. Chronic fatigue syndrome:new insights and old ignorance [J]. J Intern Med,2018,246(5):455-469.
[4] Abbey SE,Garfinkel PE. Neurasthenia and chronic fatigue syndrome:the role of culture in the making of a diagnosis [J]. Am J Psychiatry,2019,148(12):1638-1646.
[5] 钟懿珠,高静,叶艳,等.补虚劳经典药膳粥改善脾肾阳虚证慢性疲劳综合征患者临床症状研究[J].中国现代医学杂志,2018,28(36):37-43.
[6] 刘情.中医诊治慢性疲劳综合征的诊断标准[M].北京:中医研究院情报研究室,1993.
[7] 国家药监局.中药新药临床研究指导原则[Z].2018.
[8] 姚树森,范贞.《赫尔辛基宣言》修订与受试者权益保障[J].中国医院,2014,18(2):51-53.
[9] 田德禄.中医内科学[M].北京:中国中医药出版社,2003:218.
[10] 国家中医药管理局.中医病证诊断疗效标准[M].南京:南京大学出版社,1994.
[11] 韦光,李雪青,石志敏.针刺二海穴治疗慢性疲劳综合征的随机对照研究[J].针灸临床杂志,2017,33(4):42-44.
[12] 郭婷,周锐,王青云,等.穴位埋线治疗慢性疲劳综合征有效率Meta分析[J].针灸临床杂志,2019,35(10):86-90.
[13] White PD. A perspective on causation of the chronic fatigue syndrome by considering its nosology [J]. J Eval Clin Pract,2019,25(6):991-996.
[14] Knoop H,Prins JB,Moss-Morris R,et al. The central role of cognitive processes in the perpetuation of chronic fatigue syndrome [J]. J Psychosom Res,2017,68(5):489-494.
[15] 柯智淳,王燕燕,张玮,等.慢性疲劳综合征免疫学发病机制及针灸推拿治疗研究近况[J].辽宁中医杂志,2020, 11(9):1052-1053.
[16] 王洁琼,韩一豪,纳森,等.中药及针灸治疗慢性疲劳综合征的机制研究进展[J].环球中医药,2018,23(9):1483-1488.
[17] Craig T,Kakumanu S. Chronic fatigue syndrome:evaluation and treatment [J]. Am Fam Physician,2019,65(6):1083-1090.
[18] Demitrack MA,Greden JF. Chronic fatigue syndrome:the need for an integrative approach [J]. Biol Psychiatry,2018,30(8):747-752.
[19] Watanabe Y,Kuratsune H. History of researches on myalgic encephalomyelitis/chronic fatigue syndrome [J]. Brain Nerve,2018,70(1):5-9.
[20] 付玉娜,李佩哲,刘陨君,等.背部推拿结合针刺及药物疗法治疗慢性疲劳综合征失眠[J].吉林中医药,2019, 39(7):969-971.
[21] 颜宇轩,潘畅,吴节,等.针灸周期疗法治疗脾肾阳虚型卵泡发育不良疗效研究[J].中国针灸,2017,37(1):39-44.
[22] 范湘旭,黄娜娜,陈亚军,等.针灸治疗脾肾两虚型慢性疲劳综合征的临床观察[J].中医药导报,2019,15(2):126-128.
[23] 张宝文,翟恒,苑迅.针灸治疗慢性疲劳综合征临床研究现况[J].辽宁中医药大学学报,2017,26(10):180-182.
[24] Williams TE,Chalder T,Sharpe M,et al. Heterogeneity in chronic fatigue syndrome-empirically defined subgroups from the PACE trial [J]. Psychol Med,2017,47(8):1454-1465.
[25] Matsuda Y,Matsui T,Kataoka K,et al. A two-year follow-up study of chronic fatigue syndrome comorbid with psychiatric disorders [J]. Psychiatry Clin Neurosci,2017, 63(3):365-373.