Abstract:Objective To understand Professor Xia Guicheng’s prescription drug use of traditional Chinese medicine decoction pieces in menstrual period in the treatment of infertility, and to explore and study the characteristics and rules of its drug use. Methods A total of 984 prescriptions of traditional Chinese medicine decoction pieces in menstrual period for infertility treated by Professor Xia Guicheng in Affiliated Hospital of Nanjing University of Chinese medicine from September 2016 to September 2017 were selected to conduct data sorting, and high-frequency drugs, high-frequency drug pairs, menstrual return and basic prescriptions in the prescriptions were analyzed to explore their characteristics of drug use. Results The single traditional Chinese medicine with the frequency of more than 10% included 20 herbs, such as Paeoniae Radix Rubra, Lycopi Herba, stir-baking with bran Atractylodis rhizoma, Salviae Miltiorrhizae; processing with vinegar Cyperi Rhizoma, Leonuri Herba and Poria. Among them, drugs for promoting blood circulation for removing blood stasis were used most frequently, followed by regulating qi-flowing drugs, heat-clearing drugs, eliminating dampness drugs and tonifying deficiency drugs. Twenty-six high-frequency drug pairs included Paeoniae Radix Rubra and Lycopi Herba, Paeoniae Radix Rubra and stir-baking with bran Atractylodis rhizoma, Paeoniae Radix Rubra and Salviae Miltiorrhizae, etc. Drugs belonging to the liver channel were used most. The basic formula was stir-baking with bran Atractylodis rhizoma, Paeoniae Radix Rubra, Dipsaci Radix, Salviae Miltiorrhizae, Poria, Cinnamomi Cortex, processing with vinegar Cyperi Rhizoma, Leonuri Herba, Lycopi Herba. Conclusion Professor Xia Guicheng often uses drugs such as promoting blood circulation for removing blood stasis, regulating qi-flowing, eliminating dampness and tonifying deficiency to treat infertility during menstrual period. Menstrual period treatment focuses on promoting blood circulation for regulating menstruation, tonifying the kidney and warming Yang, and activating qi flowing and eliminating dampness.
庞会明 姚毅 杜萍. 夏桂成教授治疗不孕症行经期用药特点分析[J]. 中国医药导报, 2021, 18(16): 129-132,136.
PANG Huiming YAO Yi DU Ping. Analysis on the characteristics of menstrual period drug use in the treatment of infertility by Professor Xia Guicheng. 中国医药导报, 2021, 18(16): 129-132,136.