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针药结合治疗腰椎间盘突出症的效果
洪秋阳      刘晓静      王桂玲
北京中医医院顺义医院针灸科,北京   101300
Effect of acupuncture combined with medicine on lumbar disc herniation
HONG Qiuyang   LIU Xiaojing   WANG Guiling
Department of Acupuncture and Moxibustion, Shunyi Hospital, Beijing Hospital of Traditional Chinese Medicine, Beijing 101300, China
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摘要 目的 观察针药结合治疗腰椎间盘突出症的临床效果。 方法 将2017年6月—2019年6月北京中医医院顺义医院收治的80例腰椎间盘突出症患者按照随机数字表法分为观察组和对照组,每组40例。对照组给予独活寄生汤口服治疗,观察组在对照组的基础上联合针刺“王氏腰痛八针”治疗。观察并比较两组患者治疗前、治疗2周后及随访3个月时疼痛视觉模拟评分(VAS)、日本骨科协会评估治疗分数(JOA)、Oswestry功能障碍指数评分(ODI),以及血清中疼痛相关介质水平的变化,并比较两组治疗后的临床效果。 结果 两组治疗2周后及随访3个月时JOA、ODI、VAS评分均较治疗前升高,且观察组高于对照组(均P < 0.05);两组治疗后血清PGE2、5-HT水平较治疗前均降低,β-EP水平较治疗前升高(均P < 0.05),观察组治疗后PGE2、5-HT水平均低于对照组,血清β-EP水平高于对照组,差异有均统计学意义(均P < 0.05)。观察组治疗后总有效率高于对照组(P < 0.05)。 结论 针刺联合独活寄生汤治疗可显著改善腰椎间盘突出症患者的临床症状,调节疼痛介质水平,并具有较好的远期疗效。
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洪秋阳 刘晓静 王桂玲
关键词 腰椎间盘突出针刺腰痛八针独活寄生汤疼痛介质    
Abstract:Objective To observe the clinical efficacy of acupuncture combined with medicine in the treatment of lumbar disc herniation. Methods A total of 80 patients with lumbar disc herniation admitted to Shunyi Hospital, Beijing Hospital of Traditional Chinese Medicine from June 2017 to June 2019 were divided into observation group and control group by random number table method, with 40 cases in each group. The control group was given Duhuo Jisheng Decoction orally; the observation group was treated with “Wang’s lumbago eight needles” on the basis of the control group. The changes of visual analogue scale (VAS), Japanese orthopaedic association acores (JOA), Oswestry disability index score (ODI), and the level of pain related mediators in serum were observed and compared between the two groups before treatment, after two weeks of treatment and tree months of follow-up. Results The JOA, ODI and VAS scores in both groups after two weeks of treatment and three months of follow-up were higher than those before treatment, and observation group was higher than control group (all P < 0.05). After treatment, serum PGE2 and 5-HT levels in two groups were lower than before treatment, and β-EP levels in two groups were higher than before treatment (all P < 0.05). After treatment, PGE2 and 5-HT levels in observation group were lower than control group, and serum β-EP level was higher than control group, the differences were all statistically significant (all P < 0.05). The total effective rate of observation group was higher than control group (P < 0.05). Conclusion Acupuncture combined with Duhuo Jisheng Decoction can significantly improve the clinical symptoms of patients with lumbar disc herniation, regulate the level of pain mediators, and has a good long-term effect.
Key wordsLumbar disc herniation    Acupuncture    Eight needlings for lumbago    Duhuo Jisheng Decoction    Pain mediators
    
基金资助:北京中医药科技发展资金项目(JJ2015-24)。
通讯作者: 王桂玲(1969-),女,主任医师;研究方向:针灸治疗疼痛疾病。   
作者简介: 洪秋阳(1983-),男,博士,副主任医师;研究方向:针灸治疗运动系统疾病和失眠。
引用本文:   
洪秋阳 刘晓静 王桂玲. 针药结合治疗腰椎间盘突出症的效果[J]. 中国医药导报, 2021, 18(12): 111-114.
HONG Qiuyang LIU Xiaojing WANG Guiling. Effect of acupuncture combined with medicine on lumbar disc herniation. 中国医药导报, 2021, 18(12): 111-114.
链接本文:  
https://www.yiyaodaobao.com.cn/CN/     或     https://www.yiyaodaobao.com.cn/CN/Y2021/V18/I12/111

 

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