Relationship between TG / HDL-C ratio and the risk of coronary heart disease and its diagnostic value
YANG Lin1 GE Baiping2 JIANG Shan3 FU Qiang1 LIU Wenshu1 ZHAO Linlin4
1.Department of Internal Medicine-Cardiovascular, the People’s Hospital of Liaoning Province, Liaoning Province, Shenyang 110016, China;
2.Department of Emergency, the People’s Hospital of Liaoning Province, Liaoning Province, Shenyang 110016, China;
3.Department of Respiratory, Shengjing Hospital Affiliated to China Medical University, Liaoning Province, Shenyang 110000, China;
4.Department of Cardiac Surgery, the People’s Hospital of Liaoning Province, Liaoning Province, Shenyang 110016, China
Abstract：Objective To investigate the relationship between triglyceride / high density lipoprotein cholesterol (TG / HDL-C) ratio and the risk of coronary heart disease (CHD) and its diagnostic value. Methods One hundred patients with CHD (CHD group) and 100 patients without CHD (non-CHD group) admitted to the People’s Hospital of Liaoning Province from June 2017 to June 2019 were selected as the research objects. The differences of TG / HDL-C ratio and general data between the two groups were compared. The risk of CHD induced by TG / HDL-C ratio was analyzed by multivariate logistic regression. Receiver operating characteristic (ROC) curve was used to evaluate its diagnostic value. Results The levels of TG / HDL-C ratio and TG and the percentages of history of hypertension and family history of CHD in CHD group were significantly higher than those in non-CHD group, while the level of HDL-C was significantly lower than that in non-CHD group, the differences were statistically significant (all P ＜ 0.05). Multivariate logistic regression analysis showed that TG (OR = 1.021, P ＜ 0.001), TG/HDL-C ratio (OR = 4.231, P = 0.006), history of hypertension (OR = 5.724, P ＜ 0.001) and family history of CHD (OR = 3.614, P ＜ 0.001) were all independent risk factors for CHD, while HDL-C (OR = 0.196, P = 0.010) were protective factors. ROC curve analysis showed that among TG, HDL-C and TG/HDL-C ratios, the area under curve (AUC) of TG/HDL-C ratio was the largest (AUC=0.859, P ＜ 0.05). Conclusion The TG / HDL-C ratio of CHD patients is significantly higher than that of non-CHD patients, which has higher diagnostic value for CHD and is an independent risk factor for the occurrence of CHD.
杨林1 葛百平2 姜珊3 付强1 刘文书1 赵林林4. TG/HDL-C比值与冠心病患者致病风险的关系及诊断价值[J]. 中国医药导报, 2021, 18(11): 66-69.
YANG Lin1 GE Baiping2 JIANG Shan3 FU Qiang1 LIU Wenshu1 ZHAO Linlin4. Relationship between TG / HDL-C ratio and the risk of coronary heart disease and its diagnostic value. 中国医药导报, 2021, 18(11): 66-69.
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