Abstract:Objective To observe the occurrence of pulmonary infection in patients with stable chronic obstructive pulmonary disease (COPD), and to analyze its possible influencing factors. Methods From June 2018 to June 2020, 120 patients with stable COPD admitted to West China Hospital of Sichuan University were selected, the occurrence of pulmonary infection in patients was evaluated according to relevant standards; general information questionnaire was designed, the data such as gender and age of the patients were recorded in detail, included the possible influencing factors, the influencing factors of pulmonary infection in stable COPD patients were analyzed by univariate and multivariate tests. Results A total of 120 patients with stable COPD were evaluated, the results showed that 23 patients occurred pulmonary infection, the incidence rate was 19.17%; by single regression analysis, the results showed that combined with diabetes mellitus, smoking, use time of antibiotics ≥14 days, use time of glucocorticoid >seven days and low expression of serum albumin were the influencing factors of pulmonary infection (OR > 1, P < 0.05); then multiple regression model was established and multivariate analysis was conducted, the results showed that combined with diabetes mellitus, smoking, use time of antibiotics ≥14 days and low expression of serum albumin were the influencing factors of pulmonary infection (OR > 1, P < 0.05). Conclusion The occurrence of pulmonary infection in patients with stable COPD may be affected by combined with diabetes mellitus, smoking, prolonged use time of antibiotics and low expression of serum albumin, the above factors should be focused on clinically, and targeted intervention should be given.