Clinical effect of Qiyang Capsules on impotence in diabetes mellitus with kidney deficiency and blood stasis type
DING Qian1 ZHAO Feng2 LIU Qian1 ZHANG Qian2 YANG Xiaoli1 XU Yangtao3
1.Department of Traditional Chinese Medicine, the Second Central Hospital of Baoding, Hebei Province, Zhuozhou 072750, China;
2.Department of Rehabilitation, the Second Central Hospital of Baoding, Hebei Province, Zhuozhou 072750, China;
3.Department of Urology, the Second Central Hospital of Baoding, Hebei Province, Zhuozhou 072750, China
Abstract：Objective To study the clinical effect of Qiyang Capsules on impotence in diabetes mellitus with kidney deficiency and blood stasis type. Methods A total of 160 patients with kidney deficiency and blood stasis type diabetes mellitus impotence treated in the Second Central Hospital of Baoding, Hebei Province from March 2017 to June 2019 were selected and divided into control group and observation group by coin toss method. The control group (71 cases) received routine hypoglycemic treatment and low-dose phosphodiesterase type 5 inhibitor, and the observation group (89 cases) were treated with Qiyang Capsules, for one month. The clinical efficacy, international index of erectile function-5 (IIEF-5) score, modified sexual life quality questionnaire-quality of life (mSLQQ-QoL) score, erectile hardness (EHS) grading , sex hormone levels (testosterone [T], testosterone estradiol [E2]) before and after treatment and adverse reactions of the two groups were compared. Results The clinical efficacy of the observation group was better than that of the control group, and the difference was statistically significant (P＜0.05). After treatment, IIEF-5 and mSLQQ-QoL scores in two groups were higher than before treatment, and those in the observation group were higher than those in the control group, the differences were statistically significant (P＜0.05). After treatment, the EHS grading of the two groups was better than that before treatment, and that of the observation group was better than that of the control group, the differences were statistically significant (P＜0.05). After treatment, T level in the two groups was higher than before treatment, and that in the observation group was higher than that in the control group, E2 level in the two groups was lower than before treatment, and that in the observation group was lower than that in the control group, the differences were statistically significant (P＜0.05). There was no significant difference in the total incidence of adverse reactions between the two groups (P＞0.05). Conclusion Qiyang Capsules can effectively improve erectile function and hardness, improve sexual life quality, and regulate sex hormone level in treatment of kidney deficiency and blood stasis type diabetes mellitus impotence, without significant adverse reactions.
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