Abstract：Rheumatoid arthritis (RA) is a crippling autoimmune disease with a high prevalence and disability rate, which seriously threatens the quality of life of patients. The clinical manifestation is that active stage and remission stage appear alternately. Repeated activity accelerates the process of bone destruction. How to stabilize the condition, avoid RA activity, and achieve continuous remission is the focus and difficulty of clinical treatment. That “overexertion leading to qi consumption” is an important cause of RA activity. Prevention of insufficient consumption of qi should be carried out throughout the treatment of RA. By explaining the connotation and extension of this classical theory of traditional Chinese medicine, this paper analyzes the pathogenesis characteristics of “overexertion leading to qi consumption” in the process of inducing RA activity from the point of view of five-zang fatigue and five-body arthralgia, expounds its close relationship with the turning point event of RA activity, and links it with the pathogenesis pathology of immune imbalance and inflammatory storm, so as to provide a theoretical basis for explaining the scientific connotation of RA activity caused by “overexertion leading to qi consumption”. In order to provide reference for RA activities of comprehensive prevention and preventive treatment in traditional Chinese medicine.
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