Abstract：Objective To investigate the independent risk factors of nosocomial infection during gastric dynamic endoscopy, and to take management and control measures. Methods A total of 180 patients who underwent gastric dynamic endoscopy in Jiangsu Province Hospital from January 2019 to March 2021 were selected, diagnosed and confirmed to have been infected, and divided into infection group and non-infection group. Univariate and multivariate logistic regression analysis was used to analyze the independent risk factors of nosocomial infection during gastric dynamic endoscopy. Results Among the 180 patients, 15 patients developed infection, with an incidence rate of 8.33%. Univariate analysis showed that the ration of complicated with diabetes mellitus, application of immunosuppressants, ventilation times of cleaning and disinfection room, invasive operation, glutaraldehyde concentration, glutaraldehyde soaking time, stored in a drying cabinet, and perfused with 75%-95% ethanol in the infection group and the non-infected group, and the differences were statistical significance (P ＜ 0.05). Multivariate logistic regression analysis showed that glutaraldehyde concentration (OR = 2.286, P = 0.004), glutaraldehyde soaking time (OR = 5.717, P = 0.017), 75%-95% ethanol perfusion pipeline (OR = 5.769, P = 0.016) were independent risk factor for nosocomial infection during gastric dynamic endoscopy. Conclusion The concentration of glutaraldehyde used, the soaking time of glutaraldehyde, and the 75% to 95% ethanol perfusion pipeline are important factors that lead to nosocomial infection during gastric dynamic endoscopy. Clinical attention should be paid to the above factors, and effective and targeted endoscopic management measures should be taken to actively prevent the occurrence of nosocomial infection and reduce the incidence of nosocomial infection during gastric dynamic endoscopy.
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