皮肤多发性基底细胞癌临床与病理分析

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Abstract Objective To investigate the clinical and pathological features of multiple basal cell carcinoma in Chinese population. Methods "Multiple" and "basal cell carcinoma" were used as key words, and the retrieval time was limited from November 1985 to January 2017. Relevant literatures are retrieved in the China Journal Full-text Database (CNKI), Wanfang database, Wiper database. Cases that in different journals or repeated in different forms were removed. The sex, age, course of disease, location, pathological results and prognosis of the patients with multiple basal cell carcinoma were analyzed. Results A total of 38 literatures were retrieved, and 52 cases of multiple basal cell carcinoma were found. From 1985, 3 cases, 5 cases, 19 cases and 25 cases were reported at each stage according to the division of each 8 years. The proportion of men and women was 1.26∶1, and the range of the age was from 4 to 82 years old, of which 31 cases were over 50 years old (59.6%). The median of the course of the disease was 7 years. 7 cases were engaged in outdoor work for a long time in the 16 reported occupations. 48 cases (92.3%) were located at the site of light exposure. Among the reported lesions of 51 cases, there were 25 cases with a total number of less than 5 of lesions cases. 21 cases (40.4%) of lesion accompanied by ulceration and 33 cases of nodular ulcers (63.5%) in clinical classification. 25 cases (59.5%) were entity type of the 42 cases about the pathological classification. The coincidence rate of clinical and pathological diagnosis was 69.2%. Lymph node metastasis was found in 2 cases (3.8%). 22 cases reported for treatment, 17 cases (77.3%) were excised. There were 2 cases relapsed (13.3%) , respectively in 1 and 2 years after operation in 15 cases of follow-up and prognosis patients. Conclusion Multiple basal cell carcinoma occurs at the head, neck and upper limb in the elderly. The treatment time is late, and the rate of clinical misdiagnosis, ulcer incidence, metastasis, and recurrence are high. Surgical excision is still the main treatment. Moreover, there has an increasing number of the reported cases in the near future, it should pay more attention .

Key words： Basal cell carcinoma Clinic Pathology Multiple

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	WANG Zhiwei1
	2 ZHENG Deyi2 LI Weiren 3▲ LIU Li1 Han Qingling1 YAN Xiaoling1

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WANG Zhiwei1,2 ZHENG Deyi2 LI Weiren 3▲ LIU Li1 Han Qingling1 YAN Xiaoling1. The analysis of clinical and pathological multiple basal cell carcinoma of the skin[J]. 中国医药导报, 2018, 15(7): 86-89.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I7/86

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