阴虚风动证室性早搏动态心电图的特征分析

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Abstract Objective To observe the characteristic changes of dynamic electrocardiogram in patients who were diagnosed as premature ventricular contractions with syndromes of stirring wind due to yin deficiency. Methods From November 2011 to August 2016, 90 patients who were diagnosed as premature ventricular contractions with syndromes of stirring wind due to yin deficiency in Guang'anmen Hospital, China Academy of Chinese Medical Sciences (“our hospital” for short) were selected as the premature ventricular contraction group, and 30 healthy subjects in our hospital were selected as the control group. All subjects underwent 24 hours dynamic electrocardiogram. The average heart rate, slowest heart rate, heart rate variability (HRV) of the two groups and the number of premature ventricular contraction in morning and night of premature ventricular contraction group, the correlation between TCM syndrome classification and HRV index in the premature ventricular contraction group were observed and analyzed. Results The levels of the average heart rate and the slowest heart rate in premature ventricular contraction group were all higher than those in control group (P ＜ 0.05). The levels of standard deviation of NN intervals (SDNN), standard deviation of average 5 min NN intervals (SDANN), percentage of differences exceeding 50 ms between adjacent normal number of intervals (PNN50), square root of the mean squared differences of successive RR interval (RMSSD) and HRV trigonometric index in premature ventricular contraction group were lower than those in control group (P ＜ 0.05). The premature ventricular contraction frequency of premature ventricular contraction group in the night was more than that in the morning (P ＜ 0.05). The syndrome classification of traditional Chinese medicine in premature ventricular contraction group was positively correlated with age, which was negatively correlated with SDNN, SDANN, PNN50, RMSSD, HRV triangular index. Conclusion The premature ventricular contraction frequency of patients in premature ventricular contraction group in the night is more than that in the morning, and the HRV is lower than control group. It is speculated that the occurrence of premature ventricular contraction with syndrome of stirring wind due to yin deficiency is positively related to autonomic nerve dysfunction, mainly vagus function decline.

Key words： Premature ventricular contraction Syndromes of stirring wind due to yin deficiency Dynamic electrocardiogram Heart rate variability

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	CHEN Jin1
	2 ZHANG Limei1 SONG Qingqiao1 DU Bai1

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CHEN Jin1,2 ZHANG Limei1 SONG Qingqiao1 DU Bai1. Analysis on the characteristics of dynamic electrocardiogram of premature ventricular contractions with syndromes of stirring wind due to yin deficiency[J]. 中国医药导报, 2018, 15(6): 141-144.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I6/141

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