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| Research progress and mechanism of sepsis-induced acute kidney injury |
| ZHENG Ting YANG Dingping▲ |
| Department of Nephrology, Renmin Hospital of Wuhan University, Hubei Province, Wuhan 430060, China |
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Abstract Acute kidney injury is one of the most common and serious complications of severe sepsis. And the incidence and mortality of patients with sepsis-induced acute kidney injury (SAKI) remained high. In recent years, more and more studies have shown that the mechanism of mitochondrial dynamics, autophagy, oxidative stress and inflammatory response plays an extremely important role in the formation of SAKI. Therefore, understanding the development mechanism of SAKI is helpful for better prevention and control, and effectively reduce morbidity and mortality. In this paper, the mechanism of occurrence and development of SAKI is reviewed.
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