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| Correlation between plasma ox-LDL, AIP levels and carotid artery intima-media thickness in patients with acute cerebral infarction |
| HUANG Rui HUANG Yong LIU Xingzhao HE Ling |
| Department of Ultrasound, Jiangjin Central Hospital, Chongqing 402260, China |
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Abstract Objective To investigate the correlation between plasma oxidative low density lipoprotein (ox-LDL), atherogenic index of plasma (AIP) levels and carotid artery intima-media thickness (CIMT) in patients with acute cerebral infarction (ACI). Methods From March to August in 2016, 131 patients with ACI (case group) and 60 healthy people (control group) in Jiangjin Central Hospital were recruited. Venous blood of subjects were collected to detected total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), HDL-C, ox-LDL, and AIP was calculated, and CIMT was measured by color Doppler ultrasonic diagnostic apparatus. Results The ox-LDL, AIP and CIMT in case group were significantly higher than those in control group (P < 0.05). The ox-LDL and AIP were both in positive correlation with the CIMT (r=0.618, 0.609, P < 0.05). Conclusion The ox-LDL and AIP levels in patients with ACI are in positive correlation with the CIMT, it has important significance to predict the extent of arterial stenosis, can help to conduct resist oxidation and lipid-lowering treatment, and reduce the risk of ACI
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