|
|
Effect of comprehensive intervention on clinical efficacy and quality of life in patients with immune thrombocytopenia |
YU Youhuan ZHANG Xiaohua LIN Guoqiang ZHANG Yanming▲ |
Department of Hematology, the Affiliated Huai’an Hospital of Xuzhou Medical University (Huai’an Second People’s Hospital), Jiangsu Province, Huai’an 223001, China |
|
|
Abstract Objective To explore the effect of comprehensive nursing intervention on the clinical efficacy and quality of life of patients with immune thrombocytopenia (ITP) medication. Methods A selection of 117 ITP patients admitted to Huai’an Hospital of Xuzhou Medical University from January 2016 to October 2019 were divided into intervention group (60 cases) and control group (57 cases) according to the random number table method. All patients were given Prednison combined with recombinant human thrombopoietin, the control group was given conventional nursing intervention, while the intervention group was given comprehensive nursing intervention. The clinical efficacy, adverse reactions and quality of life of the two groups were compared after treatment for three months. Results After three months of treatment, the effective rate of the intervention group was significantly higher than that of the control group, while the incidence of adverse reactions was significantly lower than that of the control group, and the differences were statistically significant (P < 0.05). After three months of treatment, the activity, energy, pain, sleep, social life, and emotional response scores of the two groups were lower than those before treatment, while the physical activity, energy, sleep, emotional response scores of the intervention group were significantly lower than those of the control group, and the differences were highly statistically significant (P < 0.01). Conclusion Comprehensive nursing intervention can help improve the clinical efficacy of ITP drug treatment patients, reduce the incidence of adverse drug reactions, and improve the quality of life of patients.
|
|
|
|
|
[1] 刘先栋,陈玙,常姝婷,等.老年原发免疫性血小板减少症诊治进展[J].临床血液学杂志,2019,32(1):60-63.
[2] 陈玙,王梅芳,程芳芳,等.老年原发免疫性血小板减少症患者临床特征及预后分析[J].首都医科大学学报,2018, 39(2):277-281.
[3] 李红菊.大剂量激素联合重组人血小板生成素与环孢素治疗免疫性血小板减少症的疗效比较[J].中国现代医学杂志,2019,29(1):109-113.
[4] 王菱菱,陆米则,陈亨,等.重组人血小板生成素联合糖皮质激素治疗免疫性血小板减少症效果观察[J].山东医药,2016,56(22):92-93.
[5] 李洋,吕明恩,郝亚停,等.成人原发免疫性血小板减少症患者疲劳症状及影响因素分析[J].中华血液学杂志,2017,38(5):384-389.
[6] 孟欢.难治性免疫性血小板减少症患者的综合性护理干预[J].实用临床医药杂志,2018,22(18):39-42.
[7] 中华医学会血液学分会血栓与止血学组.成人原发性免疫性血小板减少症诊治的中国专家共识(2016年版)[J].中华血液学杂志,2016,37(2):89-93.
[8] Mckenna SP,Hunt SM,Mcewenn J. Weighting the scriusness of perceived health problems using Thurstone’s method of paired comparisons [J]. Int J Epidemiol,1981, 10:93-97.
[9] 张新华,徐彪,宋森花,等.原发性血小板减少症合并血栓栓塞3例报告并文献复习[J].华南国防医学杂志,2018, 32(12):860-863.
[10] 孟予城,杨淑莲,刘雅宁,等.免疫性血小板减少症发病机制的研究进展[J].医学综述,2018,24(10):117-121.
[11] 谢坤莹,魏锦,邹兴立,等.重组人血小板生成素、重组人白介素11分别联合糖皮质激素治疗成人原发性免疫性血小板减少症的疗效[J].实用医学杂志,2019,35(16):2624-2627.
[12] 张小平,吴要功,杨迪,等.57例免疫性血小板减少症临床分析[J].临床血液学杂志,2019,32(2):29-31,35.
[13] 夏正坤.糖皮质激素临床应用再认识[J].医学研究生学报,2018,31(2):113-117.
[14] 孙善芳,袁红建,潘怀富,等.重组人血小板生成素治疗原发免疫性血小板减少症的临床效果及安全性[J].交通医学,2017,31(3):258-259.
[15] 尚淑玲,尚雅静,宋金萍,等.成人原发性免疫性血小板减少症患者抑郁和焦虑状况调查[J].中国临床保健杂志,2014,17(5):545-546.
[16] Terrell DR,Reese J,Branesky D,et al. Depression in adult patients with primary immune thrombocytopenia [J]. Am J Hematol,2016,91(10):E462-E463.
[17] 程敏,王新燕,张诚.心理护理干预对中青年缺血性脑卒中患者负性情绪及依从性的影响[J].中国医药导报,2018,15(1):167-170.
[18] 刘欣艳,陈莎莎,赵婷.PDCA循环结合全程健康教育对老年高血压患者自护能力及疾病认知水平的影响[J].中国医药导报,2018,15(8):160-163,176.
[19] 张文坚,张琳,马灵甫,等.基于健康信念模式的健康教育在重症血小板减少症病人安全管理中的应用[J].循证护理,2020,6(3):273-276.
[20] 刘文凤,邓欢,傅晓凤,等.心理干预对白血病患者生存质量和心理状况影响的Meta分析[J].中国医药导报,2019,16(8):162-166.
[21] 任博环.综合护理干预对提高肾病综合征患者用药依从性的效果[J].中国现代药物应用,2019,13(18):165-166.
[22] 薛瑶琴,叶春游.综合护理干预对神经外科高血压脑出血手术患者的护理效果评价[J].中外医学研究,2020, 18(3):81-83.
[23] 陈红梅.综合性护理干预对超重及肥胖患者焦虑抑郁情绪及妊娠结局的影响[J].中国医学创新,2019,16(3):83-86.
[24] 毛丽红,崔世红,姜燕.多元化健康教育对新疆维吾尔族老年COPD患者疾病认知及健康行为的影响[J].医学临床研究,2018,35(9):1773-1775.
[25] 张建辉,曹晓明.多元化护理结合穴位贴敷疗法对于减轻首次使用无创机械通气患者幽闭恐惧症的研究[J].中国护理管理,2018,18(z1):51-52.
[26] 方华瑾,连建安.综合护理干预对乳腺癌根治术患者心理状态及生活质量的影响[J].中国现代医生,2020,58(14):166-169.
[27] 黎楚眉,郑玉玲,袁玉燕,等.老年焦虑症伴阻塞性睡眠呼吸暂停低通气综合征的综合护理干预[J].中国医药科学,2020,10(12):109-112.
[28] 刘涵,李星明,程陶朱,等.北京市失能老年人长期护理模式选择偏好及其影响因素研究[J].中华健康管理学杂志,2017,11(6):553-558.
[29] 孔一帆,陈玉瑙,潘峰.综合性护理干预对急性髓系白血病患者心理状态和生活质量的影响[J].四川解剖学杂志,2019,27(2):116-117. |
|
|
|