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| Clinical observation and effect of Salvia Tetramethylpyrazine Injection on serum homocysteine, high-sensitivity C-reactive protein and lipid levels in ischemic stroke |
| CHEN Guoning LIN Zehui DU Yongming Li Quan |
| Emergency Department, Chinese Medicine Hospital of Hainan Province, Guangzhou University of Chinese Medicine, Hainan Province, Haikou 570203, China |
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Abstract Objective To explore the effect of Salvia Tetramethylpyrazine Injection on serum homocysteine, high-sensitivity C-reactive protein and lipid levels in ischemic stroke and clinical efficacy. Methods From February 2014 to November 2016, 100 patients with ischemic stroke in the emergency department of Chinese Medicine Hospital of Hainan Province, Guangzhou University of Chinese Medicine were selected and divided into treatment group and control group according to therapeutic schedule, with 50 cases in each group. The control group was treated with conventional treatment, while the treatment group was treated Salvia Tetramethylpyrazine Injection on the basis of control group. The serum homocysteine, high-sensitivity C-reactive protein, lipid levels, clinical efficacy, NIHSS score of the two groups were observed. Results After treatment, the levels of serum homocysteine, high-sensitivity C-reactive protein , total cholesterol, triacylglycerol and lipoprotein (a) in the treatment group were lower than those in the control group, with statistically significant difference ( P ＜ 0.05). The NIHSS score and clinical efficacy of treatment group were significantly better than those of control group, with statistically significant difference (P ＜ 0.05). Conclusion Salvia Tetramethylpyrazine Injection can reduce the serum homocysteine, high sensitivity c-reactive protein and serum lipid levels in patients with ischemic stroke, improve the clinical efficacy and neurological function．
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