宫颈癌调强放疗俯卧位Belly board与仰卧位的剂量学与副反应比较

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Abstract Objective To explore the optimal position in radiotherapy for cervical cancer, by comparing the dose-volume relationship of the mid-intestinal pouch, bladder, rectum, femoral head and the occurrence of acute radiation enteritis in the prone position + Belly board and the supine position. Methods A total of 40 patients with cervical cancer who underwent intensity modulation radiotherapy in Xiangtan Central Hospital, Hu′nan Province from June 2017 to March 2019 were randomly selected. CT scans were performed in Belly board and Belly position respectively. The target area and organs at risk were mapped under the same conditions and the treatment plan was optimized to compare the dose-volume relationship between the target area and organs at risk in two positions. Then the patients were divided into prone position group (20 cases) and supine position group (20 cases) for treatment by stratified sampling and random number table method according to age and stage, and the occurrence of acute radiation enteritis was observed in the two groups. Results Compared with the supine position group, the volume of intestinal pouch of organs at risk in the prone position group was significantly reduced (P < 0.05), the average volume of bladder and rectum and the average volume of target area showed no statistical significance (P ＞ 0.05), and the comparison of target area fitness index and uniformity index showed no statistical significance (P > 0.05). Compared with the supine group, the volume of intestinal pouch receiving 25-45 Gy dose was significantly reduced in the prone position group (P ＜ 0.01), while the dose-volume relationship of other organs at risk was not statistically significant (P ＞ 0.05). The incidence of acute radiation enteritis in prone position group was significantly lower than that in supine position group, and the severity was reduced, with statistically significant difference (P ＜ 0.05). Conclusion For intensity-modulated radiotherapy of cervical cancer, the Belly board in prone position can significantly reduce the dose of intestinal pouch and reduce the occurrence of intestinal side effects.

Key words： Cervical cancer Belly board Intensity-modulated radiation therapy Position

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	ZHOU Long TANG Yan LIU Gengchun DONG Ke LIU Yuelong HUANG Baqun

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ZHOU Long TANG Yan LIU Gengchun DONG Ke LIU Yuelong HUANG Baqun. Dosimetry and side effects comparison of prone with Belly board and supine position in intensity modulated radiotherapy for cervical cancer[J]. 中国医药导报, 2020, 17(26): 86-90.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2020/V17/I26/86

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