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| Difference analysis of clinical characteristics of polycystic ovary syndrome patients with different body mass index |
| YU Jinglu1 HOU Lihui2 SUN Miao2 WANG Ying2 |
1.Graduate School, Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150036, China;
2.the Second Department of Gynecology, the First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150036, China |
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Abstract Objective To study clinical characteristics, sex hormone level, glucose metabolism level and lipid metabolism level of polycystic ovary syndrome (PCOS) patients with different body mass index (BMI), and to explore the effect of obesity on PCOS. Methods From January 2015 to August 2018, 660 patients with PCOS were selected from Gynecology Clinic in the First Affiliated Hospital of Heilongjiang University of Chinese Medicine. According to different BMI, the patients were divided into normal group (BMI 18.5-＜23.0 kg/m2) of 243 cases, overweight group (BMI 23.0-＜25.0 kg/m2) of 100 cases, obesity group (BMI ≥ 25 kg/m2) of 317 cases. Clinical characteristics, sex hormone, glucose and lipid metabolism were compared among three groups. Results There were no significant differences in age and hirsutism among three groups (P > 0.05). There were significant differences in systolic blood pressure, diastolic blood pressure, waist circumference, hip circumference, waist hip ratio, acne and black acanthosis among three groups (P < 0.05). The levels of follicle stimulating hormone, luteinizing hormone, follicle stimulating hormone/luteinizing hormone, testosterone, rostenedione and sex hormone binding globulin were significantly different among three groups (P < 0.05). There were no significant differences in estradiol and dehydroepiandrosterone sulfate among three groups (P > 0.05). There were significant differences in fasting blood glucose, fasting insulin and insulin resistance index among three groups (P < 0.05). There were significant differences in triglyceride, total cholesterol, high density lipoprotein cholesterol and low density lipoprotein cholesterol among three groups (P < 0.05). Conclusion In obese PCOS patients, fat distribution is abdominal obesity, androgen level is higher, glucose and lipid metabolism disorder is more obvious.
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