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| Effect of Yiqi Huayu and Pinggan Zishen Decoction on heart and kidney function in patients with hypertension retinopathy |
| ZHANG Qiaona1 FANG Fang2 CAO Yan2 |
1.Department of Emergency, Tangshan Traditional Chinese Medicine Hospital, Hebei Province, Tangshan 063000, China;
2.Department of Cardiovascular Medicine, Tangshan Traditional Chinese Medicine Hospital, Hebei Province, Tangshan 063000, China |
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Abstract Objective To investigate the effect of Yiqi Huayu and Pinggan Zishen Decoction on heart and kidney function in patients with hypertension retinopathy (HRP). Methods One hundred and sixty HRP patients treated in Tangshan Traditional Chinese Medicine Hospital from June 2017 to June 2018 were selected and divided into control group and observation group according to random digital table method, with 80 cases in each group, of which, two cases fell off in control group and one case in observation group. Control group was given Western medicine basic hypotension and Western medicine complication symptomatic treatment, on the basis of conventional Western medicine treatment, observation group was added with Yiqi Huayu and Pinggan Zishen Decoction, treatment course of two groups was one month. Clinical efficacy, traditional Chinese medicine syndrome efficacy, cardiac and renal function indexes [serum creatinine (Scr), blood urea nitrogen (BUN), brain natriuretic peptide (BNP), ejection fraction (EF)] were observed in two groups. Results Clinical total effective rate and traditional Chinese medicine syndrome total effective rate of observation group were higher than those of control group, the differences were statistically significant (P < 0.05). After treatment, BNP level of two groups was lower than that before treatment, EF was higher than that before treatment, BNP level of observation group was lower than that of control group, EF was higher than that of control group, the differences were statistically significant (P < 0.05). After treatment, Scr and BUN levels of two groups were lower than those before treatment, and observation group was lower than that of control group, the differences were statistically significant (P < 0.05). Conclusion Conventional Western medicine basic treatment combined with Yiqi Huayu and Pinggan Zishen Decoction has significant effect in improving heart and kidney function in patients with HRP, which is worthy of clinical promotion.
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