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| Analysis of high risk factors of pulmonary infection in patients with pulmonary tuberculosis during hospitalization |
| LI Shunli1 LIU Yang2 |
1.Office of Infection Management, Beijing Chao-yang Hospital, Capital Medical University, Beijing 100043, China;
2.Department of Disease Control, Beijing Chest Hospital, Capital Medical University, Beijing 101149, China |
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Abstract Objective To analysis the high risk factors of pulmonary infection in patients with pulmonary tuberculosis during hospitalization. Methods The clinical data of 400 patients with pulmonary tuberculosis confirmed in Beijing Chao-yang Hospital, Capital Medical University from January 2015 to December 2018 were analyzed retrospectively. According to whether pulmonary infection occurred, they were divided into control group (uninfected, 328 cases) and study group (infected, 72 cases). The high risk factors of pulmonary infection caused by pulmonary tuberculosis complications were screened. Results The age ≥60 years, course ≥5 years, smoking history, diabetes history, cavitary tuberculosis, number of lung fields involved ≥3, retreatment of tuberculosis, hemoptysis, anemia, long-term use history of glucocorticoids, long-term use history of broad-spectrum antibiotics and invasive operation in the study group were significantly higher than those in the control group, and the differences were statistically significant (P ＜ 0.05). The retreatment of pulmonary tuberculosis, cavitary tuberculosis, diabetes history, long-term use history of glucocorticoids and long-term use history of broad-spectrum antibiotics were all high risk factors of pulmonary tuberculosis complicated with pulmonary infection (OR ＞ 1, P ＜ 0.05). Conclusion Pulmonary tuberculosis patients are more likely to be complicated with pulmonary infection. Retreatment of pulmonary tuberculosis, cavitary pulmonary tuberculosis, diabetes mellitus, long-term use of glucocorticoids and broad-spectrum antibiotics are the high risk factors of pulmonary tuberculosis complicated with pulmonary infection. Clinical intervention measures should be taken to reduce the incidence of pulmonary infection.
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