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| Mining regularity of professor Ba Yuanming′s prescription in the treatment of chronic renal failure based on the auxiliary platform of traditional Chinese medicine inheritance |
| LIU Shi1 GAO Yue1 CHEN Shuhe1 HUANG Zhengde1 LI Chengyin2 |
1.Department of Pharmacy, Hubei Provincial Hospital of Traditional Chinese Medicine, Hubei Province, Wuhan 430061, China;
2.Department of Oncology, Hubei Provincial Hospital of Traditional Chinese Medicine, Hubei Province, Wuhan 430061, China |
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Abstract Objective To provide the comprehensive basis for prevention and treatment for chronic renal failure (CRF) through analyzing the herbal administration experience for treating CRF of professor Ba Yuanming by utilizing traditional Chinese medicine inheritance support platform software. Methods From January 2016 to January 2017, the prescriptions for treating CRF applied by professor Ba Yuanming in Hubei Provincial Hospital of Traditional Chinese Medicine were collected, and the database of relevant traditional Chinese medicine prescriptions were constructed based on traditional Chinese medicine inheritance support platform software. Additionally, the frequency statistics, association rules and composing formulas of herbs and prescriptions via the approaches of Apriori algorithm and entropy clustering. Results Totally, 298 prescriptions were enrolled in current research, involving 123 different kinds of herbs. The frequently adopted herbs were Radix Astragali seu Hedysari, Poria, Radix Codonopsis, Rhizoma Dioscoreae, Fructus Corni, and so on. Besides, the medicinal properties were mainly sweet, bitter in the five flavors, cold and flat were appeared most in four qi, while in meridians, they were mainly kidney, liver, spleen, liver meridians. It could be preliminarily concluded that professor Ba was good at using Zhibai Dihuang Pills and Shenqi Dihuang Decoction. And the results emerged 6 new traditional Chinese medicine prescriptions. Conclusion Therapeutic principle and method of professor Ba Yuanming for treating CRF mainly including regulating spleen and stomach, strengthening kidneys, promoting blood circulation to remove blood stasis. Also, professor Ba pays attention to regulate triple warmer, strengthening and restoring effects.
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