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| Effect of Chinese medicine starvation-free fasting therapy on glucolipid metabolism and liver fat deposition in patients with nonalcoholic fatty liver disease |
| YANG Maoqin1 XUE Jingdong2 LI Fenping2 DONG Lu2 FU Qilin2 |
1.The First School of Clinical Medicine, Shaanxi University of Chinese Medicine, Shaanxi Province, Xianyang 712046, China;
2.Department of Hepatopathy, Shaanxi Provincial Hospital of Chinese Medicine, Shaanxi Province, Xi′an 710003, China |
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Abstract Objective To study the efficacy of Chinese medicine starvation-free fasting therapy on nonalcoholic fatty liver disease (NAFLD) and its effects on glucolipid metabolism and liver fat deposition. Methods A total of 124 inpatients with NAFLD from October 2018 to March 2019 in Shaanxi Provincial Hospital of Chinese Medicine were selected and divided into two groups according to the random number table method, with 62 cases in each group. Fasting group was treated with Chinese medicine starvation-free fasting therapy, and routine group was given Western medicine, and two groups were treated for 2 weeks. The clinical efficacy, Chinese medicine syndrome scores, body surface measurement indicators, glucolipid metabolism and liver fat deposition were compared between two groups, and the occurrence of adverse reactions was observed. Results The clinical efficacy in fasting group was significantly better than that in routine group (P < 0.05). After treatment, Chinese medicine syndrome scores in two groups were significantly reduced (P < 0.05), and the scores in fasting group were lower than those in routine group (P < 0.05). After treatment, fasting blood-glucose, total cholesterol and triacylglycerol were significantly decreased in two groups (P < 0.05), which in fasting group were lower than those in routine group (P < 0.05). After treatment, controlled attenuation parameter, liver stiffness measurement and liver fat content in two groups were significantly decreased (P < 0.05), which in fasting group were lower than those in routine group (P < 0.05). Conclusion Chinese medicine starvation-free fasting therapy for NAFLD is beneficial to alleviate the symptoms and weight of patients, improve glucolipid metabolism and reduce liver fat deposition. And its clinical efficacy is superior to routine western medicine.
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