腰硬联合阻滞分娩镇痛对子痫前期孕妇分娩及产后脑钠肽和高敏感性肌钙蛋白T的影响

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Abstract Objective To observe the effect of lumbar stiffness combined block for labor analgesia on brain natriuretic peptide (BNP) and high sensitivity troponin T (cTnT-hs) in preeclampsia pregnant women during delivery and postpartum. Methods From January 2017 to December 2018, 120 cases with preeclampsia pregnant women who were hospitalized in Department of Anesthesiology, Nanning Maternal and Child Health Hospital, Guangxi Zhuang Autonomous Region were selected as research object. According to the random number table methcd, they were divided into observation group and control group, with 60 cases in each group. Control group was treated with routine spasmolysis, antihypertensive, while observation group was treated with lumbar stiffness combined block for labor analgesia on the basis of control group. Natural childbirth pregnant women of observation group were recorded as the observation subgroup, natural childbirth pregnant women of control group were recorded as the control subgroup. BNP and cTnT-hs levels were compared in the two subgroups during the incubation period, the active period, the second stage of labor, 2 h after delivery and the 42nd day after delivery, and the occurrence of blood pressure on the 42nd day after delivery were recorded in the two subgroups. Results There were 45 natural childbirth pregnant women in the observation group and 39 natural childbirth pregnant women in the control group. BNP levels at different stages of labor in the observation subgroup were lower than those in the control subgroup, and the differences were statistically significant (all P < 0.05). There were no significant differences in cTnT-hs between the two subgroups at different stages of labor (P > 0.05). Conclusion Lumbar stiffness combined block for labor analgesia can reduce the delivery process and post-delivery BNP level of pre-eclampsia pregnant women, reduce the incidence of hypertension on the 42nd day after delivery, and reduce the rate of cesarean section.

Key words： Preeclampsia Labor analgesia Brain natriuretic peptide High sensitivity troponin T； Postpartum hypertension

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	LAO Chengyi ZHU Maoling WANG Zongjie HUANG Ling JIANG Xun

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LAO Chengyi ZHU Maoling WANG Zongjie HUANG Ling JIANG Xun. Effect of lumbar stiffness combined block for labor analgesia on brain natriuretic peptide and high sensitivity troponin T in preeclampsia pregnant women during delivery and postpartum[J]. 中国医药导报, 2020, 17(4): 127-130.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2020/V17/I4/127

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