带状疱疹患者皮肤温度觉阈值变化及意义的临床研究

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Abstract Objective To measure and quantitative analyze the thermal sensation thresholds of the affected side and healthy side skin of herpes zoster patients，in order to understand the function of primary afferent fibers in the patients with herpes zoster. Methods From December 2015 to February 2017, 80 cases with herpes zoster who admitted to Department of Pain, the First Affiliated Hospital of Chongqing Medical University as research objects. TSA-Ⅱ thermal sensation analyzer was used to detect the cold sensation (CS), warm sensation (WS), cold pain sensation (CP) and heat pain sensation (HP) thresholds by using the method of limits. Statistical analysis was performed and Pearson correlation analysis was used to analyze the correlation between the thermal sensation thresholds of the affected sides of herpes zoster patients and the course of disease, numerical rating scale (NRS), ID pain scores. Results The CS and CP thresholds on the affected side were lower than those on the healthy side, and the HP thresholds were higher than those on the healthy side, and the differences were statistically significant (all P < 0.05). There was no significant difference in the WS thresholds between the two sides (P > 0.05). The CS and CP thresholds of the affected side were negatively correlated with the course of disease (r = -0.399, -0.374, P < 0.05). Conclusion The thermal sensation thresholds testing is one of the objective methods to evaluate the function of C and Aδ primary afferent fibers, which is beneficial to diagnose and evaluate the severity of peripheral nerve damage of the disease.

Key words： Herpes zoster A&delta primary afferent fibers C primary afferent fibers Thermal sensation thresholds

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	LI Nan YANG Xiaoqiu▲

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LI Nan YANG Xiaoqiu▲. Clinical study on the changes and significance of thermal sensation thresholds in patients with herpes zoster[J]. 中国医药导报, 2020, 17(4): 110-112,116.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2020/V17/I4/110

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