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| Study of the methods of reducing the use of pain-relieving drugs during perioperative period of total knee arthroplasty |
| GUO Jianbin1 WEN Zhenkun2 WANG Yakang1 LI Kun1 WU Yanjie1 LIU Rui1 ZHANG Yumin1 |
1.Department of Joint Surgery, Honghui Hospital Affiliated to Xi＇an Jiaotong University Medical College, Shaanxi Province, Xi'an 710054, China;
2.The Second Clinical College, Shaanxi University of Chinese Medicine, Shaanxi Province, Xianyang 712046, China |
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Abstract Objective To investigate the intervention of non-drug method for postoperative pain in total knee arthroplasty, in order to clarify whether perioperative non-drug therapy can relieve pain in postoperative patients and reduce the use of Celecoxib. Methods 203 patients underwent unilateral total knee arthroplasty in Department of Joint Surgery, Honghui Hospital Affiliated to Xi′an Jiaotong University Medical College from January 2016 to September 2017 were selected, then they were divided into group A (Celecoxib ＜ 800 mg, 105 cases) and group B (Celecoxib ≥ 800 mg, 98 cases), according to whether the dosage of oral Celecoxib was ≥ 800 mg. The risk factors of increase the use of Celecoxib were investigated by single-factor analysis and multifactor Logistic regression analysis. Results The cases of general anesthesia + femoral nerve block anesthesia, "cocktail" intra-articular injection and postoperative psychological comfort, electrotherapy, cryotherapy in the group A were more than those in the group B, with statistically significant difference (P < 0.05). Multifactor Logistic regression analysis showed: general anesthesia + femoral nerve block, "cocktail" intra-articular injection and postoperative psychological comfort, electrotherapy were independent risk factors of increase the use of Celecoxib (P < 0.05). Conclusion The application of general anesthesia + femoral nerve block anesthesia, "cocktail" joint cavity injection and postoperative psychological comfort, electrotherapy can alleviate postoperative pain and reduce the use of analgesic drugs after total knee arthroplasty.
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