关节镜下同种异体半月板移植治疗半月板缺损的体会

Abstract
Figure/Table
References (20)
Related Citation (15)

Download: PDF (768 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the clinical efficacy of arthroscopic allogeneic meniscus transplantation in the treatment of meniscus defects. Methods Fifteen patients with meniscus defects received from the Department of Orthopedics, Guangzhou Red Cross Hospital and the Second People′s Hospital of Shenzhen from January 2016 to March 2017 were selected. All patients underwent the same allogeneic meniscus transplantation under arthroscopy. Postoperative follow-up was conducted, including joint symptoms and signs, knee imaging examination results, and Lysholm knee score. Results All the 15 patients were followed up for 8 to 16 months, with an average of (12.50±0.50) months. 93.33% of the patients had no obvious symptoms of discomfort in the knee joint and were able to take care of themselves, 6.67% of the patients developed effusion in the joint cavity 6 months after the operation, which affected the function of the knee joint. The pain was intense, and the effusion disappeared after repeated drainage, and the pain was relieved. The imaging results showed that there was no change in the postoperative knee joint space in 93.33% patients, no osteophyte formation and necrosis occurred around them, and there was a small amount of effusion in the joint cavity and local uplift in 6.67% patients. Lysholm knee score before and after surgery was compared at different time points, and the difference was statistically significant (F = 6.478 , P ＜ 0.05), and the 3, 6 months and 12 months after the operation were all improved compared with the pre-operation, the difference was statistically significant (P ＜ 0.05). Conclusion The clinical effect of allogeneic meniscus transplantation under arthroscopy for meniscus defect is better, and it has important application value.

Key words： Arthroscopy Allogeneic meniscus transplantation Knee joint

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	WANG Min1 WANG Wen1 LI Ying2 MENG Qingqi1 YANG Weimin1 LI Siming1

Cite this article:

WANG Min1 WANG Wen1 LI Ying2 MENG Qingqi1 YANG Weimin1 LI Siming1. Experience in the treatment of meniscus defect by allogeneic meniscus transplantation under arthroscopy[J]. 中国医药导报, 2020, 17(3): 78-81.

URL:

http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2020/V17/I3/78

[1] Vundelinckx B，Bellemans J，Vanlauwe J. Arthroscopically assisted meniscal allograft transplantation in the knee： a medium-term subjective，clinical，and radiographical outcome evaluation [J]. Am J Sports Med，2010，38（11）：2240-2247.
[2] Roumazeille T，Klouche S，Rousselin B，et al. Arthroscopic meniscal allograft transplantation with two tibia tunnels without bone plugs：evaluation of healing on MR arthrography and functional outcomes [J]. Knee Surg Sports Traumatol Arthrosc，2015，23（1）：264-269.
[3] 章亚东，侯树勋，张轶超，等.关节镜下异体半月板移植微创手术初步报告[J].中华创伤骨科杂志，2008，10（3）：218-222.
[4] Berhouet J，Marty F，Rosset P，et al. Meniscus matching：evaluation of direct anatomical，indirect radiographic，and photographic methods in 10 cadaver knees [J]. Orthop Traumatol Surg Res，2013，99（3）：291-297.
[5] Wang H，Gee AO，Hutchinson ID，et al. Bone Plug Versus Suture-Only Fixation of Meniscal Grafts： Effect on Joint Contact Mechanics During Simulated Gait [J]. Am J Sports Med，2014，42（7）：1682-1689.
[6] Faivre B，Boisrenoult P，Lonjon G，et al. Lateral meniscus allograft transplantation：Clinical and anatomic outcomes after arthroscopic implantation with tibial tunnels versus open implantation without tunnels [J]. Orthop Traumatol Surg Res，2014，100（3）：297-302.
[7] Abat F，Gelber PE，Erquicia JI，et al. Prospective comparative study between two different fixation techniques in meniscal allografttransplantation [J]. Knee Surg Sports Traumatol Arthrosc，2013，21（7）：1516-1522.
[8] Vundelinckx B，Vanlauwe J，Bellemans J. Long-term Subjective，Clinical，and Radiographic Outcome Evaluation of Meniscal Allograft Transplantation in the Knee [J]. Am J Sports Med，2014，42（7）：1592-1599.
[9] Lubowitz JH，Verdonk Pc，Reid JB，et al. Meniscus a1-lografttransplantation：a current concepts review[J]. Knee Surg Sports Traumatol Arthrosc，2007，15（5）：476-492.
[10] Peters G，Wirth CJ. The current state of IneIliscal allografttransplantation and replacement [J]. Knee，2003，10（1）：19-31.
[11] Sharma RR，Pollock K，Hubel A，et al. Mesenchymalstem or stromal cells：a review of clinicalapplications and manufacturing practices [J]. Transfusion，2014，54（5）：1418-1437.
[12] Shimomura K，Ando W，Moriguchi Y，et al. Next generation mesenchymal stem cell（MSC）-basedcartilage repair using scaffold-free tissue engineeredconstructs generated with synovial mesenchymal stemcells [J]. Cartilage，2015， 6（2Suppl）：13S-29S.
[13] 卫旭东，党源，胡德庆.间充质干细胞在软骨损伤修复中的研究进展[J].中华细胞与干细胞杂志：电子版，2017， 7（3）：178-184.
[14] Whitehouse MR，Howells NR，Parry MC，et al. Repair of torn avascular meniscal cartilage using undifferentiatedautologous mesenchymal stem cells：from invitro optimization to a frst-in-human study [J]. Stem Cell Transl Med，2017，6（4）：1237-1248.
[15] Yeo RWY，Chai R，Hian K，et al. Exosome：a noveland safer therapeutic refnement of mesenchymal stemcell [J].Intech，2013，1（7）：1-12.
[16] Koh YG，Choi YJ. Infrapatellar fat pad-derived mesenchymalstem cell therapy for knee osteoarthritis [J]. Knee，2012，19（6）：902-907.
[17] 侯立刚，杨建义.组织工程技术修复半月板损伤：从基础到临床的差距[J].中国组织工程研究，2016，20（11）：1651-1657.
[18] 张鹏飞，徐永胜，包呼日查，等.膝关节半月板根部损伤的治疗进展[J].中国医药，2018，13（5）：793-796.
[19] 田林，戴七一，戴子一，等.外科手法对兔膝骨关节炎模型软骨组织的影响[J].风湿病与关节炎，2017，6（10）：68-73.
[20] Kon YG，Kwon OR，Kim YS，et al. Comparativeoutcomes of open-wedge high tibial osteotomy withplatelet-rich plasma alone or incombination with mesenchymalstem cell treatment：a prospective study [J]. Arthroscopy，2014， 30（11）：1453-1460