缺血性脑卒中后认知功能障碍生物学标志物及预测因子研究进展

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Abstract Cognitive impairment after ischemic stroke is an important part of post-stroke disability, which not only increases the mortality rate of patients, but also seriously affects patients′ daily living ability and social function. A large number of biomarkers such as enzymes, serum, cerebrospinal fluid, inflammatory mediators, hormones, genotypes and RNA profiles have been shown to predict cognitive impairment after ischemic stroke. In addition, neuroimaging, cerebrovascular disease and its risk factors such as blood pressure, blood glucose, renal function and other abnormal indicators are related to cognitive dysfunction. The paper reviews the known biomarkers and predictors to provide a basis for the prediction and diagnosis of cognitive impairment after ischemic stroke.

Key words： Enzymology Serology Genetics Images Vascular disease

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	GAO Manman YAN Bingchun

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GAO Manman YAN Bingchun. Research progress in biomarkers and predictors of cognitive impairment after ischemic stroke[J]. 中国医药导报, 2020, 17(3): 26-29,37.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2020/V17/I3/26

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