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| Comparative study of ABCD2 and ABC2D2 in predicting risk of stroke after transient ischemic attack |
| WANG Weiqiang YU Hui ZHAO Bin ZHU Ruifang |
| Department of Neurology, Suzhou Municipal Hospital Affiliated to Anhui Medical University, Anhui Province, Suzhou 234000, China |
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Abstract Objective To explore the predictive value of ABCD2 criteria and ABC2D2 criteria method for stroke risk in transient ischemic attack (TIA). Methods One hundred and thirty-nine patients with TIA from March 2014 to September 2016 in Suzhou Municipal Hospital Affiliated to Anhui Medical University were divided into low risk, moderate risk and high risk group according to ABCD2 and ABC2D2 criteria, the incidence of stroke in 7 d and 1 year was observed. The stratification of the risk of stroke risk in patients with TIA was evaluated. The prediction value of the risk of stroke in 7 d, 1 year after TIA was compared under the ROC curve (AUC). Results According to the ABCD2 criteria, the patients were divided into 37 cases of low-risk group (0-3 points), 86 cases of middle-risk group (4-5 points) and 16 cases of high-risk group (6-7 points). The risk of stroke in 7 days was 5.41%, 26.74% and 56.25%, the risk of stroke in 1 year was 13.51%, 40.70% and 68.75%, the differences were statistically significant (P ＜ 0.05). According to the ABC2D2 criteria, the patients were divided into 24 cases of low-risk group (0-3 points), 78 cases of middle-risk group (4-6 points) and 37 cases of high-risk group (7-9 points). The risk of stroke in 7 d was 0.00%, 16.67% and 56.76%, the risk of stroke in 1 year was 4.17%, 30.77% and 70.27%, the differences were statistically significance (P ＜ 0.05). ABC2D2 criteria were used to predict that the area of the ROC curve of the risk of stroke in patients with TIA in 7 d (1 year) was higher than that of ABCD2, the differences were statistically significance (P ＜ 0.05). Conclusion The prediction value of ABC2D2 criteria is higher than that of the ABCD2 scoring method, which is a more effective method to predict the risk of stroke after TIA.
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| [1] Cutting S，Regan E，Lee VH，et al. High ABCD2 Scores and In-Hospital Interventions following Transient Ischemic Attack [J]. Cerebrovasc Dis Extra，2016，6（3）：76-83.
[2] Lee J，Shah K. In Patients Presenting With Transient Ischemic Attack，Does the ABCD2 Clinical Prediction Rule Provide Adequate Risk Stratification for Clinical Decisionmaking in the Emergency Department? [J]. Ann Emerg Med，2013，62（1）：14-15.
[3] Kakkos SK，Nicolaides AN，Charalambous I，et al. Predictors and clinical significance of progression or regression of asymptomatic carotid stenosis [J]. J Vasc Surg，2014，59（4）：956-967.
[4] Rong X，Yang W，Garzon-Muvdi T，et al. Risk Factors Associated with Ipsilateral Ischemic Events Following Carotid Endarterectomy for Carotid Artery Stenosis [J]. World Neurosurg，2016，89（1）：611-619.
[5] Easton JD，Saver JL，AIhers GW，et al. American Heart Association；American stroke Association Stroke Council；Council on Cardiovascular Surgery and Anestbesia；Council on Cardiovascular Radiology and Intervention；Council on Cardiovascular Nursing；Interdisciplinary Council on Peripheral Vascular Disease. Definition and evaluation of transient ischemic attack：a scientific statement for healthcare professionals from the American Heart Association/American Stroke Association Stroke Council；The American Academy of Neurology affirms the value of this statement as an educatioml tool for neurologists [J]. Stroke，2009， 40（6）：2276-2293.
[6] Kiyohara T，Kamouchi M，Kumai Y，et al. ABCD3 and ABCD3-I scores are superior to ABCD2 score in the prediction of short-and long-term risks of stroke after transient ischemic attack [J]. Stroke，2014，45（2）：418-425.
[7] Li CC，Tong T，Yang YM，et al. Prognostic value of the ABCD2 score on long-term follow-up of transient ischemic attack using the new tissue-based definition [J]. Neurology Asia，2015，20（1）：15-21.
[8] Wang YY，Song B，Fang H，et al. Validation of ABCD3 score in the predication of stroke risk after transient ischemic attack [J]. Zhonghua Yi Xue Za Zhi，2013，93（43）：3424-3427.
[9] 李静，李长清.ABCD2评分联合血浆同型半胱氨酸水平检测在短暂性脑缺血发作风险评估中的应用[J].中国医药导报，2016，13（13）：36-39.
[10] Zhao M，Wang S，Zhang D，et al.Comparison of Stroke Prediction Accuracy of ABCD2 and ABCD3-I in Patients with Transient Ischemic Attack：A Meta Analysis [J]. J Stroke Cerebrovasc Dis，2017，26（10）：2387-2395.
[11] Valls J，Peiro-Chamarro M，Cambray S，et al. A Current Estimation of the Early Risk of Stroke after Transient Ischemic Attack：A Systematic Review and Meta Analysis of Recent Intervention Studies [J]. Cerebrovasc Dis，2016， 43（1/2）：90-98.
[12] Long B，Koyfman A. Best Clinical Practice：Controversies in Transient Ischemic Attack Evaluation and Disposition in the Emergency Department [J]. J Emerg Med，2016，52（3）：299-310.
[13] Uehara T，Minematsu K，Ohara T，et al. Incidence，predictors and etiology of sub-sequent ischemic stroke within one year after transient ischemic attack [J]. Int J Stroke，2016，12（1）：84-89.
[14] Cutting S，Regan E，Lee VH，et al. High ABCD2 Scores and In-Hospital Interventions following Transient Ischemic Attack [J]. Cerebrovasc Dis Extra，2016，6（3）：76-83.
[15] Akijian L，NíChróinín D，Callaly E，et al. Why do transient ischemic attack patients have higher early stroke recurrence risk than those with ischemic stroke? Influence of patient behavior and other risk factors in the North Dublin Population Stroke Study [J]. Int J Stroke，2016，12（1）：96-104.
[16] Li OL，Silver FL，Lichtman J，et al. Sex Differences in the Presentation，Care，and Outcomes of Transient Ischemic Attack：Results From the Ontario Stroke Registry [J]. Stroke，2015，47（1）：255-257.
[17] van Hoof RHM，Schreuder FHBM，Nelemans P，et al. Ischemic Stroke Patients Demonstrate Increased Carotid Plaque Microvasculature Compared to（Ocular）TransientIschemic Attack Patients [J]. Cerebrovasc Dis，2017，44（5/6）：297-303.
[18] Wang Y，Liu M，Pu C. 2014 Chinese guidelines for secondary prevention of ischemic stroke and transient ischemic attack [J]. Int J Stroke，2017，12（3）：302-320.
[19] Al-Khaled M，Scheef B. Symptomatic carotid stenosis and stroke risk in patients with transient ischemic attack according to the tissue-based definition [J]. Int J Neurosci，2016，126（10）：888-892.
[20] Johansson E，Wester P. Recurrent stroke risk is high after a single cerebrovascular event in patients with symptomatic 50-99% carotid stenosis：a cohort study [J]. BMC Neurol，2014，4（14）：23-30.
[21] Seo WK，Kim YJ，Lee J，et al. Design and Rationale of the Intima-Medial Thickness Sub-Study of the PreventIon of CArdiovascular Events in iSchemic Stroke Patients with High Risk of Cerebral hemOrrhage（PICASSO-IMT）Study [J]. J Stroke Cerebrovasc Dis，2017，26（9）：1892-1898. |
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