静脉注射利多卡因在无痛胃镜检查中的临床应用

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Abstract Objective To evaluate the effects of intravenous infusion of Lidocaine on Propofol requirements, incidence of cardiopulmonary adverse events, recovery of post-gastroscopy. Methods From November 2018 to February 2019, a total of 180 consecutive patients undergoing painless gastroscopy in the First Affiliated Hospital of Anhui Medical University were enrolled in the study, while they were divided into Lidocaine group and control group according to the random number table method, with 90 cases in each group. Patients in Lidocaine group were slowly injected with 2% Lidocaine at 1.5 mg/kg, while the equal volume of 0.9% normal saline was given in control group 2 min before induction. Propofol induction, supplementation and total dose, cardiopulmonary adverse events and local anesthetic intoxication, recovery of post-gastroscopy were recorded. Results The requirements of Propofol induction and total dose of Lidocaine group were significantly lower than those of control group, and the incidence of hypotension was lower than that of control group, while the times of postoperative wake-up, response, and free movement of Lidocaine group were significantly shorter than those in control group, and the differences were statistically significant (P ＜ 0.05). There were no significant differences in body movement, respiratory depression, and residence time in the resuscitation area between the two groups (P ＞ 0.05). Local anesthetic intoxication was not observed. Conclusion Intravenous injection of Lidocaine in painless gastroscopy can reduce Propofol requirements, obtains stability hemodynamics during gastroscopy and accelerates post-gastroscopy recovery.

Key words： Intravenous Lidocaine Propofol Adverse events Gastroscopy

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	TANG Lili GU Erwei▲

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TANG Lili GU Erwei▲. Clinical application of intravenous infusion of Lidocaine in painless gastroscopy[J]. 中国医药导报, 2019, 16(35): 139-142.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2019/V16/I35/139

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