外周血NLR对急性呼吸窘迫综合征患者预后的预测价值

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Abstract Objective To study the prognostic value of the ratio of neutrophil count (NC) to lymphocyte count (LC) (NLR) in patients with acute respiratory distress syndrome (ARDS). Methods Clinical data of 80 patients with ARDS admitted to Liaohe Oilfield General Hospital from February 2015 to February 2019 was retrospectively analyzed. All patients were divided into survival group (36 cases) and death group (44 cases) according to clinical outcome after 28 days. The baseline data, oxygenation index (PaO2/FiO2), acute physiology and chronic health (APACHE Ⅱ) score and assessment of sequential organ failure (SOFA) score were counted and compared between two groups. White blood cell count (WBC), neutrophil count (NC), lymphocyte count (LC), NLR and procalcitonin (PCT) levels were compared between two groups, and multivariate Logistic regression analysis was performed for prognosis. The predictive value of NLR and PCT in the prognosis of ARDS patients was analyzed by receiver operating characteristic curve (ROC). Results PaO2/FiO2 level in survival group was higher than that in death group, while APACHE Ⅱ and SOFA scores in survival group were lower than those in death group (P < 0.05). There was no significant difference in WBC and NC between two groups (P > 0.05); LC level in survival group was higher than that in death group (P < 0.05); NLR and PCT levels in survival group were lower than those in death group (P < 0.05). Multiple Logistic regression analysis showed that NLR and PCT were independent risk factors of ARDS (P < 0.05). NLR was superior to PCT in predicting the prognosis of ARDS (P < 0.05). Conclusion The increase of NLR in peripheral blood is a risk factor for the prognosis of ARDS patients. The detection of NLR level is helpful to evaluate the prognosis of ARDS patients.

Key words： Acute respiratory distress syndrome Neutrophil count Lymphocyte count Predictive value Prognosis

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	MA Yanquan YU Hongzhi TIAN Lei GE Xu

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MA Yanquan YU Hongzhi TIAN Lei GE Xu. Predictive value of peripheral blood NLR in patients with acute respiratory distress syndrome[J]. 中国医药导报, 2019, 16(35): 119-122,134.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2019/V16/I35/119

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