儿童中耳炎循证指南AGREEⅡ质量评价情况

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Abstract Objective To evaluate the quality of clinical practice guidelines for otitis media in children, and to identify high quality guidelines for clinicians and pharmacists. Methods China National Knowledge Infrastucture, Wanfang Chinese Periodical Database, VIP Chinese Periodical Database, CBM database, PubMed database, Excerpta Medica Database and relevant websites, such as medlive.cn, GIN, AAP, NGC, NICE were searched by computer ranged from January 2000 to June 2019. Chinese search terms were otitis media, guidelines for clinical practice and children while English search terms were otitis media, middle ear, glue ear, guideline, guidance, child and children. Clinical practice guidelines for otitis media in children were included, appraisal of guidelines research and evaluation in Europe (AGREEⅡ) instrument was used to evaluate the quality of clinical practice guidelines. Results Ten guidelines were included, 5 of them were evidence-based (EB) guidelines, and 5 were non-EB guidelines. The consistency of 10 guidelines rated by three researchers was high. The evaluation results were as followed: the UK (ICC = 0.876, F = 22.271, P ＜ 0.001), the USA 1(ICC = 0.861, F = 19.509, P ＜ 0.001)，the USA 2 (ICC = 0.819, F = 14.587, P ＜ 0.001)，Japan (ICC = 0.853, F = 18.531, P ＜ 0.001)，Korea (ICC = 0.856, F = 18.894, P ＜ 0.001)，New South Wales (ICC = 0.865, F = 20.277, P ＜ 0.001)，China (ICC = 0.836, F = 16.258, P ＜ 0.001), Canada 1 (ICC = 0.894, F = 26.342, P ＜ 0.001)，Canada 2 (ICC = 0.880, F = 22.997, P ＜ 0.001), the international guideline (ICC = 0.795, F = 12.605, P ＜ 0.001), the differences were statistically significant. The overall quality of the 10 guidelines was not high. One was at grade A, four were at grade B, and five were at grade C. In each field, “clarity” and “scope and purpose” scored high (70.2% and 67.8% respectively), while “editorial independence” and “application” scored relatively low (34.0% and 29.7% respectively). Conclusion The quality of the included guidelines is relatively low. The quality of clinical practice guidelines for otitis media in children in China is not high. It is recommended to adopt EB methods to develop EB guidelines that are consistent with China′s national conditions.

Key words： Otitis media Guideline Children Appraisal of guidelines research and evaluation in Europe

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	DING Xiangyu1 ZHANG Guying1 WANG Weixiu2 LI Ruihong1

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DING Xiangyu1 ZHANG Guying1 WANG Weixiu2 LI Ruihong1. Quality evaluation of guidelines on otitis media in children based on AGREEⅡ[J]. 中国医药导报, 2019, 16(30): 114-117.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2019/V16/I30/114

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