老年女性桡骨远端骨折患者的骨代谢指标检测分析及再发骨折的危险因素探讨

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Abstract Objective To investigate the bone metabolism of elderly female patients with distal radius fracture and the risk factors of recurrent fracture. Methods From February 2017 to October 2018, retrospective analysis was conducted on the data of 182 elderly female patients with distal radius fracture admitted to Shijiazhuang No. 3 Hospital. Bone metabolism indexes were detected after admission. The risk factors of recurrent fracture were analyzed. Results Patients with serum alkaline phosphatase (ALP), bone gta-protein (BGP), collagen type Ⅰ N terminal peptide (NTX-Ⅰ) level were （37.56±5.83）U/L,（3.89±1.05）μg/L, （38.47±5.56）nmol/L, respectively. The incidence recurrent hair fracture was 18.68%, older age, body mass index (BMI) < 18 kg/m2, BMI > 25 kg/m2, with type 2 diabetes, osteoporosis, with lower limb joint disease, serum ALP ＜ 40 U/L, serum BGP < 4.8 μg/L, serum NTX-Ⅰ > 20 mmol/L, live alone are independent risk factors for recurrence of bone (OR = 5.512, 6.265, 5.697, 6.659, 7.776, 6.062, 7.367, 6.699, 6.966, 7.135, P ＜ 0.05). Bone grafting, early load exercise, and calcium salt use were all independent protective factors for recurrent fractures (OR = 0.511, 0.457, 0.475, P ＜ 0.05). Conclusion Elderly women with distal radius fracture are often accompanied by abnormal bone metabolism, and advanced age can increase the risk of recurrent fracture. Abnormal bone metabolism is an independent risk factor, while bone grafting is a protective factor.

Key words： Elderly women Distal radius fractures Bone metabolism Recurrent fractures Risk factors

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	LI Yan CHANG Junying▲ MU Weilu JIA Dongzhao

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LI Yan CHANG Junying▲ MU Weilu JIA Dongzhao. Detection and analysis of bone metabolic indexes in elderly female patients with distal radius fractures and discussion of risk factors for recurrent fractures[J]. 中国医药导报, 2019, 16(30): 89-92.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2019/V16/I30/89

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